anti-Filamin C, gamma (FLNC) Antibodies

FLNC encodes one of three related filamin genes, specifically gamma filamin. Additionally we are shipping FLNC Kits (33) and FLNC Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FLNC 68794 Q8VHX6
FLNC 362332  
FLNC 2318 Q14315
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Top anti-FLNC Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FLNC Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Kidney Tissue. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Western Blot: FLNC Antibody [NBP1-89300] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: FLNC Antibody [NBP1-89300] - Staining of human cell line U-2 OS shows positivity in plasma membrane & cytoplasm. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded Mouse heart, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with Filamin 2 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining. 100 μL Log in to see 14 to 21 Days
$306.90
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Kidney tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated ELISA, WB FLNC polyclonal antibody (A01), Lot # FAK0070504QCS1 Western Blot analysis of FLNC expression in NIH/3T3 . Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit HRP IHC (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

FLNC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FLNC Antibodies

  1. Human Polyclonal FLNC Primary Antibody for ICC, IF - ABIN4312164 : Valdés-Mas, Gutiérrez-Fernández, Gómez, Coto, Astudillo, Puente, Reguero, Álvarez, Morís, León, Martín, Puente, López-Otín: Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy. in Nature communications 2014 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal FLNC Primary Antibody for ELISA, WB - ABIN560923 : Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins. in Genes to cells : devoted to molecular & cellular mechanisms 2013 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal FLNC Primary Antibody for WB - ABIN2789843 : Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. in JACC. Basic to translational science 2016 (PubMed)

More Antibodies against FLNC Interaction Partners

Mouse (Murine) Filamin C, gamma (FLNC) interaction partners

  1. HSPB7 (show HSPB7 Antibodies) is essential for maintaining muscle integrity, which is achieved through its interaction with FLNC

  2. The data of this study presented here provide further support that FLNC, a muscle-specific protein (show TXLNB Antibodies), could be a potential novel player in FTD (show FTL Antibodies) pathogenesis.

  3. Aciculin (show PGM5 Antibodies) interacts with filamin C and Xin (show XIRP1 Antibodies) and is essential for myofibril assembly.

  4. KY, IGFN1 and FLNC are part of a Z-band associated protein complex likely to provide structural support to the skeletal muscle sarcomere.

  5. filamin C may function in signal transduction or cellular migration of the myogenic progenitor cell population

  6. These data provide the first evidence that FLNc has a crucial role in muscle development and maintenance of muscle structural integrity and suggest the presence of a TRIO (show TRIO Antibodies)-FLNc-dependent pathway in maintaining proper myotube structure.

  7. MuRF3 (show TRIM54 Antibodies) has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 (show FHL2 Antibodies) and gamma-filamin contributes to this cardioprotective function of MuRF3 (show TRIM54 Antibodies)

  8. Cbl (show CBL Antibodies)-associated protein provides another link between the myofibril cytoskeleton and the plasma membrane of muscle cells, and it may play a dynamic role in the regulation and maintenance of muscle structural integrity

Human Filamin C, gamma (FLNC) interaction partners

  1. a novel variant in FLNC was identified as pathogenic variant for familial Restrictive cardiomyopathy.

  2. The study confirms that truncating variants on myofibrillar myopathies- causing genes are frequently associated with dilated cardiomyopathies and also suggest that FLNC mutations could be considered as a common cause of dilated cardiomyopathy.

  3. Study found a novel splice-site mutation in FLNC gene (c.2389+1G>A) which co-segregated with all symptomatic individuals in the family with dilated cardiomyopathy (DCM). These results strongly suggest that the involvement of FLNC gene, due to haploinsufficiency, should be considered in familial cases with DCM, especially if accompanied with arrhythmia and increased incidence of sudden cardiac death.

  4. Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rac1/cdc42 (show CDC42 Antibodies) activites in esophageal squamous cell carcinoma.

  5. Data show that the filamin C (FLNC) protein was significantly overexpressed with the development of hepatocellular carcinoma (HCC (show FAM126A Antibodies)), which might play an important role in HCC (show FAM126A Antibodies) invasion and metastasis.

  6. Missense variant in FLNC gene is associated with reading disability.

  7. suggest that the combination of the OBSCN (show OBSCN Antibodies) p.Arg4444Trp variant and of the FLNC c.5161delG mutation, can cooperatively affect myofibril stability and increase the penetrance of muscular dystrophy in the French family

  8. This study therefore identifies both BAG3 (show BAG3 Antibodies) reduction and autophagy promotion as potential therapies for FLNC(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  9. Biallelic variants in FLNC can cause congenital dilated cardiomyopathy.

  10. Truncating mutations in FLNC caused an overlapping phenotype of dilated and left-dominant arrhythmogenic cardiomyopathies complicated by frequent premature sudden death

FLNC Antigen Profile

Protein Summary

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Filamin C, gamma (FLNC) Antibodies

  • filamin C (FLNC) antibody
  • filamin C L homeolog (flnc.L) antibody
  • filamin C (flnc) antibody
  • filamin C, gamma (Flnc) antibody
  • filamin C (Flnc) antibody
  • 1110055E19Rik antibody
  • ABP-280 antibody
  • ABP280A antibody
  • ABPA antibody
  • ABPL antibody
  • FLN2 antibody
  • MFM5 antibody
  • MPD4 antibody

Protein level used designations for anti-Filamin C, gamma (FLNC) Antibodies

filamin C, gamma (actin binding protein 280) , gamma filamin , filamin C, gamma , filamin-C-like , ABP-280-like protein , ABP-L , FLN-C , actin binding protein 280 , actin-binding protein 280 , actin-binding-like protein , filamin, gamma , filamin-2 , filamin-C , gamma-filamin , ABP-L, gamma filamin , filamin 2 , 260kDa actin-binding protein , cgABP260 actin-binding domain

GENE ID SPECIES
463711 Pan troglodytes
734178 Xenopus laevis
100329116 Xenopus (Silurana) tropicalis
100475857 Ailuropoda melanoleuca
68794 Mus musculus
362332 Rattus norvegicus
2318 Homo sapiens
100730013 Cavia porcellus
100518997 Sus scrofa
482266 Canis lupus familiaris
528415 Bos taurus
395260 Gallus gallus
101104655 Ovis aries
Selected quality suppliers for anti-FLNC (FLNC) Antibodies
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