Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1) ELISA Kits

The protein encoded by FRAT1 belongs to the GSK-3-binding protein family. Additionally we are shipping FRAT1 Antibodies (33) and FRAT1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FRAT1 14296 P70339
FRAT1 10023 Q92837
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More ELISA Kits for FRAT1 Interaction Partners

Mouse (Murine) Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1) interaction partners

  1. Gsk3b (show GSK3b ELISA Kits) is exported from the nucleus in a complex with Frat. Loss of PI3K/Akt (show AKT1 ELISA Kits) activity results in dissociation of this complex and retention of Gsk3b (show GSK3b ELISA Kits) in the nucleus.

  2. Data show that that Frat synergizes with Diversin (show ANKRD6 ELISA Kits) in the activation of JNK (show MAPK8 ELISA Kits)/AP-1 (show JUN ELISA Kits) signaling.

  3. FRAT has a role in mediating GSK-3 (show GSK3b ELISA Kits) nuclear export in mouse cells

  4. Data suggest that recruitment of Axin (show AXIN1 ELISA Kits) and Frat1 to the membrane by LRP5 (show LRP5 ELISA Kits)-triggered Wnt3 (show WNT3 ELISA Kits) signaling leads to both Axin (show AXIN1 ELISA Kits) degradation and Frat1-mediated inhibition of glycogen synthase kinase-3 (show GSK3a ELISA Kits).

Human Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1) interaction partners

  1. The results of the present study suggest that nuclear FRAT1 activates the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway and confers an increase in prostate cancer cell growth.

  2. These data suggest a potential role for targeting FRAT1 in the prevention of hypoxia-induced HCC (show FAM126A ELISA Kits) cancer progression and metastasis mediated by epithelial-to-mesenchymal transition

  3. FRAT1 and ABCG2 (show ABCG2 ELISA Kits) overexpression is associated with carcinogenesis, progression, and poor prognosis in patients with Pancreatic ductal adenocarcinoma.

  4. Positive ROR2 (show ROR2 ELISA Kits) and FRAT1 expression is associated with the progression and poor prognosis of chondrosarcoma.

  5. FRAT1 overexpression correlates with pathologic grade, proliferation, invasion and angiogenesis in brain gliomas.

  6. The mechanism of inhibiting beta-catenin (show CTNNB1 ELISA Kits) phosphorylation involves the NDRG1 (show NDRG1 ELISA Kits)-mediated upregulation of the GSK3beta (show GSK3b ELISA Kits)-binding protein FRAT1.

  7. These results highlight the potential role of FRAT1 in tumorigenesis and progression of glioblastoma.

  8. The overexpression of Frat1 and beta-catenin (show CTNNB1 ELISA Kits) was correlated with tumor differentiation, TNM (show ODZ1 ELISA Kits) stage, lymph node metastasis, and poor prognosis of NSCLC.

  9. Down-regulation of Frat1 expression reduced invasive ability in A549 cell line, further supporting idea that Frat1 may play crucial role in carcinogenesis, tumor invasiveness and dissemination in human lung cancer.

  10. Elevated expression of FRAT1 was associated with astrocytomas.

FRAT1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.

Gene names and symbols associated with FRAT1

  • FRAT1, WNT signaling pathway regulator (FRAT1) antibody
  • GSK-3 binding protein FRAT1 (frat1) antibody
  • frequently rearranged in advanced T cell lymphomas (Frat1) antibody
  • frequently rearranged in advanced T-cell lymphomas (FRAT1) antibody
  • frequently rearranged in advanced T-cell lymphomas 1 S homeolog (frat1.S) antibody
  • AW060382 antibody
  • frat1 antibody
  • gbp antibody

Protein level used designations for FRAT1

GSK-3 binding protein FRAT1 , frequently rearranged in advanced T-cell lymphomas , gsk3-binding protein , FRAT-1 , frequently rearranged in advanced T-cell lymphomas 1 , proto-oncogene FRAT1 , GSK-3 binding protein GBP , GSK-3-binding protein , gsk binding protein

466169 Pan troglodytes
705609 Macaca mulatta
100303596 Saccoglossus kowalevskii
14296 Mus musculus
10023 Homo sapiens
486819 Canis lupus familiaris
398043 Xenopus laevis
505664 Bos taurus
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