FRAT1 Products
(Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
Categories
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008].
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Featured FRAT1 Categories
FRAT1 Antibodies
High quality antibodies with extensive validation data.
FRAT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FRAT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FRAT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN2565539
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (1)
Cat. No.
ABIN6261815
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN5534285
Quantity
400 μL
Datasheet
Datasheet
Recommended FRAT1 ELISA Kits
Recommended FRAT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2565261
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3080321
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3120971
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FRAT1 products
: "The clinical significance of FRAT1 and ABCG2 expression in pancreatic ductal adenocarcinoma." in: Tumour biology, (2015) (PubMed).: "Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours." in: British journal of cancer, Vol. 94, Issue 5, pp. 686-91, (2006) (PubMed).
: "FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35021-9, (2006) (PubMed).
: "Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14066-73, (2003) (PubMed).
Synonyms and alternative names related to FRAT1
FRAT1, WNT signaling pathway regulator (FRAT1), GSK-3 binding protein FRAT1 (frat1), frequently rearranged in advanced T cell lymphomas (Frat1), frequently rearranged in advanced T-cell lymphomas (FRAT1), frequently rearranged in advanced T-cell lymphomas 1 S homeolog (frat1.S), AW060382, FRAT1, frat1, gbpProtein level used designations for FRAT1
- GSK-3 binding protein FRAT1
- frequently rearranged in advanced T-cell lymphomas
- gsk3-binding protein
- FRAT-1
- frequently rearranged in advanced T-cell lymphomas 1
- proto-oncogene FRAT1
- GSK-3 binding protein GBP
- GSK-3-binding protein
- gsk binding protein
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