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FRAT1 Products

(Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008].

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Featured FRAT1 Categories

FRAT1 Antibodies

High quality antibodies with extensive validation data.

FRAT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FRAT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FRAT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN5534284
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN5534285
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN2565539
Quantity 100 μg
Datasheet Datasheet

Recommended FRAT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1152999
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1152998
Quantity 96 tests
Datasheet Datasheet

Recommended FRAT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080321
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120971
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2565261
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our FRAT1 products

Yuan, Yang, Miao, Li, Liu, Zou: "The clinical significance of FRAT1 and ABCG2 expression in pancreatic ductal adenocarcinoma." in: Tumour biology, (2015) (PubMed).

Wang, Hewitt, Liu, Zhou, Zhu, Zhou, Zhang, Quan, Bai, Xu: "Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours." in: British journal of cancer, Vol. 94, Issue 5, pp. 686-91, (2006) (PubMed).

Hagen, Cross, Culbert, West, Frame, Morrice, Reith: "FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35021-9, (2006) (PubMed).

Hino, Michiue, Asashima, Kikuchi: "Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14066-73, (2003) (PubMed).

Synonyms and alternative names related to FRAT1

FRAT1, WNT signaling pathway regulator (FRAT1), GSK-3 binding protein FRAT1 (frat1), frequently rearranged in advanced T cell lymphomas (Frat1), frequently rearranged in advanced T-cell lymphomas (FRAT1), frequently rearranged in advanced T-cell lymphomas 1 S homeolog (frat1.S), AW060382, FRAT1, frat1, gbp

Protein level used designations for FRAT1

  • GSK-3 binding protein FRAT1
  • frequently rearranged in advanced T-cell lymphomas
  • gsk3-binding protein
  • FRAT-1
  • frequently rearranged in advanced T-cell lymphomas 1
  • proto-oncogene FRAT1
  • GSK-3 binding protein GBP
  • GSK-3-binding protein
  • gsk binding protein
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