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GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. Additionally we are shipping GDP Dissociation Inhibitor 1 Kits (27) and GDP Dissociation Inhibitor 1 Proteins (13) and many more products for this protein.
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Human Polyclonal GDI1 Primary Antibody for WB - ABIN1881368
Massignan, Biasini, Lauranzano, Veglianese, Pignataro, Fioriti, Harris, Salmona, Chiesa, Bonetto: Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway. in Molecular & cellular proteomics : MCP 2010
Show all 4 Pubmed References
Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA (human, human recombinant, or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA.
Human oligodendrogliomas cells stably expressing mutant GDI1 showed altered cell proliferation.
GDI1 mutations cause an unspecific phenotype characterized by cognitive deficits of variable degree in males, and to a lesser degree in female carriers.
A model by which mutant PrP (show C4BPA Antibodies) induces overexpression of GDI, activating a cytotoxic feedback loop that leads to protein accumulation in the secretory pathway.
RhoGDI (show ARHGDIA Antibodies) has a role in inactivating Rho GTPases with ExoS RhoGAP (show ARHGAP1 Antibodies)
isoprenylcysteine carboxylmethyltransferase (show ICMT Antibodies) regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI (show ARHGDIA Antibodies) through TNFA (show TNF Antibodies)
RhoGDI (show ARHGDIA Antibodies) overexpression is associated with paclitaxel resistance in ovarian cancers
The results of case-control analysis indicated that, no association between the rs11549300 polymorphisms of GDI1 and children NSMR (P >0.05), but its polymorphisms may be related to intelligence levels of children in Qinba region (P =0.03).
GDI-1 is preferentially involved in insulin (show INS Antibodies)-stimulated glucose transporter 4 (GLUT4 (show SLC2A4 Antibodies)) translocation through facilitating Rab10 (show RAB10 Antibodies) recycling.
Study used cognitive protocols with high translational validity to human condition that target the functionality of cortico-striatal circuitry such as attention and stimulus selection ability with progressive degree of complexity; showed that that Gdi1-null mice are impaired in attention and associative learning processes.
Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA/Gdi1 (human or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA/Gdi1.
A pivotal role of alphaGDI via specific RAB (show HRB Antibodies) GTPases acting specifically in forebrain regions at the pre-synaptic sites involved in memory formation.
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
rab GDP dissociation inhibitor alpha
, guanosine diphosphate dissociation inhibitor 1
, mental retardation, X-linked 48
, protein XAP-4
, rab GDI alpha
, rab GDP-dissociation inhibitor, alpha
, GDP dissociation inhibitor 2
, SMG p25A GDI
, GDP-dissociation inhibitor 1
, Rab GDIalpha