GDI1 antibody (C-Term)

Catalog No. ABIN2792293

The Rabbit Polyclonal anti-GDI1 antibody (ABIN2792293) specifically detects GDI1 in WB. The antibody is reactive with Human, Mouse, Rabbit, Sheep, Zebrafish (Danio rerio), Guinea Pig and Horse samples.

Quick Overview for GDI1 antibody (C-Term) (ABIN2792293)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reactivity: Human, Mouse, Rabbit, Sheep, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GDI1 Antibody

Binding Specificity: C-Term

Purpose: GDI1 Antibody - C-terminal region

Sequence: VFCSCSYDAT THFETTCNDI KDIYKRMAGT AFDFENMKRK QNDVFGEAEQ

Predicted Reactivity: Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Sheep: 92%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against GDI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GDI1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Alternative Name: GDI1

Background:

Background Information: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

Gene Name: GDP dissociation inhibitor 1

Alternative Symbols: 1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA

Protein Name: Rab GDP dissociation inhibitor alpha

Molecular Weight: 51kDa

Gene ID: 2664

NCBI Accession: NP_001484

UniProt: P31150