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GPN1 encodes a guanosine triphosphatase enzyme. Additionally we are shipping GPN1 Proteins (8) and and many more products for this protein.
Showing 10 out of 53 products:
Results show that Gpn1-inhibitable, nuclear polyubiquitination on lysine 216 regulates the half-life of Gpn3 by tagging it for proteasomal degradation.
an acquired PDZ-binding motif in Gpn3 Q279* caused Gpn3 nuclear entry, and inhibited Gpn1 nuclear export and Gpn3-mediated RNAPII nuclear targeting.
GPN1 gene variation is associated with oral cavity and pharyngeal cancer.
Gpn1-Gpn3 interaction was essential to maintain steady-state protein levels of both GTPases
A highly active, evolutionarily conserved nuclear export sequences in XAB1/Gpn1, was identified.
Data show that GPN1/GPN3 define a new family of small GTPases that are specialized for the transport of RNA polymerase II into the nucleus.
RPAP4/GPN1 is a member of a newly discovered GTPase family that contains a highly conserved GPN loop motif that is essential, along with its GTP-binding motifs, for nuclear localization of POLR2A/RPB1 in a process that also requires microtubule assembly
relieves MBD2-mediated transcriptional repression and reactivates transcription from methylated promoters
This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described.
ATP(GTP)-binding protein , MBD2-interacting protein , RNA polymerase II associated protein 4 , XPA binding protein 1, GTPase , XPA binding protein 1 , GPN-loop GTPase 1 , XPA-binding protein 1 , methyl-CpG binding domain protein 2 interacting protein