anti-GRB2-Related Adaptor Protein (GRAP) Antibodies

GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. Additionally we are shipping GRAP Proteins (5) and GRAP Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
GRAP 363616  
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Top anti-GRAP Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GRAP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Grap Antibody Dilution: 1.0ug/ml Sample Type: Rat Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184595 (0.3µg/ml) staining of human thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293/MCF-7/COLO cells, using GRAP Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$455.40
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using GRAP, antibody at 1:500 dilution. IHC-P Image Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP, antibody at 1:100 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$181.73
Details
Hamster Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: GRAP Antibody [NBP2-16737] - Sample (30 ug of whole cell lysate) A: MCF-7 12% SDS PAGE gel, diluted at 1:2000. Immunohistochemistry-Paraffin: GRAP Antibody [NBP2-16737] - Immunohistochemical analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details

GRAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GRAP Antibodies

  1. Human Polyclonal GRAP Primary Antibody for ELISA, WB - ABIN256861 : Fathi, Rasouli, Yeganeh, Salekdeh, Baharvand: Efficient differentiation of human embryonic stem cells toward dopaminergic neurons using recombinant LMX1A factor. in Molecular biotechnology 2015 (PubMed)
    Show all 2 Pubmed References

More Antibodies against GRAP Interaction Partners

Human GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. A compound mutation consisting of a large deletion and a nonsense mutation, which provides a new insight in the mutation type of CTSC (show CTSC Antibodies) gene.

  2. CTSC (show CTSC Antibodies) gene missense mutation is responsible for Papillo- Lefevre syndrome in a Turkish family.

  3. analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C (show CTSC Antibodies)

  4. Mutation screening of the CTSC (show CTSC Antibodies) gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC (show CTSC Antibodies)) gene.

  5. Neutrophilic Cathepsin C (show CTSC Antibodies) Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  6. CTSC (show CTSC Antibodies) was associated with albuminuria in type 2 diabetes patients.

  7. Homozygous mutation 901G>A in exon 7 of CTSC (show CTSC Antibodies) gene is associated with Papillon-Lefevre syndrome.

  8. Results identify a missense mutation in CTSC (show CTSC Antibodies) gene that segregate within a family with Papillon-Lefevre syndrome.

  9. Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C (show CTSC Antibodies) gene.

  10. CatC (show CTSC Antibodies) has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta (show TGFB1 Antibodies)-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2 (show GRB2 Antibodies), acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk (show EPHB2 Antibodies) pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 (show MYO15 Antibodies) domain-containing adapters Grb2 (show GRB2 Antibodies) and Grap

GRAP Antigen Profile

Protein Summary

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GRAP

  • GRB2-related adaptor protein (GRAP) antibody
  • cathepsin C (CTSC) antibody
  • GRB2-related adaptor protein (Grap) antibody
  • GRB2-related adapter protein (LOC489534) antibody
  • GRB2-related adaptor protein a (grapa) antibody
  • GRB2-related adaptor protein b (grapb) antibody
  • GRB2-related adapter protein (LOC100727005) antibody
  • 8430435N19Rik antibody
  • BB233594 antibody
  • CPPI antibody
  • DPP-I antibody
  • DPP1 antibody
  • DPPI antibody
  • Grap antibody
  • HMS antibody
  • JP antibody
  • JPD antibody
  • MGC109892 antibody
  • PALS antibody
  • PDON1 antibody
  • PLS antibody
  • si:dkeyp-9d4.1 antibody
  • zgc:110202 antibody

Protein level used designations for GRAP

GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein , cathepsin J , dipeptidyl peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , GRB2-related adaptor protein

GENE ID SPECIES
10750 Homo sapiens
1075 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
416523 Gallus gallus
489534 Canis lupus familiaris
534491 Bos taurus
553596 Danio rerio
555184 Danio rerio
100727005 Cavia porcellus
Selected quality suppliers for anti-GRAP (GRAP) Antibodies
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