GRAP antibody (C-Term)

Catalog No. ABIN2855869

Product Details anti-GRAP Antibody

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to GRAP (GRB2-related adaptor protein)
GRAP antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRAP. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GRAP

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Alternative Name: GRB2 related adaptor protein (GRAP Products)

Synonyms: 8430435N19Rik antibody, BB233594 antibody, GRAP antibody, grap antibody, zgc:110202 antibody, MGC109892 antibody, si:dkeyp-9d4.1 antibody, Grap antibody, GRB2-related adaptor protein antibody, GRB2-related adapter protein antibody, GRB2-related adaptor protein a antibody, GRB2-related adaptor protein b antibody, GRAP antibody, Grap antibody, LOC489534 antibody, grapa antibody, grapb antibody, LOC100727005 antibody

Background: This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Molecular Weight: 25 kDa

Gene ID: 10750

UniProt: Q13588