anti-Gasdermin B (GSDMB) Antibodies

GSDMB encodes a member of the gasdermin-domain containing protein family. Additionally we are shipping Gasdermin B Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GSDMB 55876 Q8TAX9
GSDMB    
GSDMB    
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Top anti-Gasdermin B Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-GSDML Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.95 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$527.50
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GSDMB Antibody (Center) in HL-60, MDA-MB435 cell line lysates (35ug/lane). GSDMB (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of GSDMB Antibody (Center) (ABIN652499) in HL-60, MDA-MB435 cell line lysates (35 µg/lane). GSDMB (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of GSDMB Antibody in HL-60, MDA-MB435 cell line lysates (35ug/lane) 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of GSDML expression in Hela (A), HT29 (B), mouse liver (C), rat liver (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IF, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.95 KDa) . Dilution: 1:500~1000 GSDML monoclonal antibody (M05), clone 1E10. Western Blot analysis of GSDML expression in A-431 ( (# ABIN394662 ) Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB GSDML antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details

Top referenced anti-Gasdermin B Antibodies

  1. Human Polyclonal Gasdermin B Primary Antibody for WB - ABIN652499 : Das, Miller, Beppu, Mueller, McGeough, Vuong, Karta, Rosenthal, Chouiali, Doherty, Kurten, Hamid, Hoffman, Broide: GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation. in Proceedings of the National Academy of Sciences of the United States of America 2018 (PubMed)

  2. Horse (Equine) Polyclonal Gasdermin B Primary Antibody for WB - ABIN2775462 : Adams, Leavitt, Holmes: Strabismus surgery for internuclear ophthalmoplegia with exotropia in multiple sclerosis. in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus 2009 (PubMed)

More Antibodies against Gasdermin B Interaction Partners

Human Gasdermin B (GSDMB) interaction partners

  1. These results showed that the PBC susceptibility allele of rs12946510 disrupted the enhancer region for ORMDL3 and GSDMB gene expression (Fig. 6). Chromatin interaction between the sequence that contains rs12946510 and the upstream sequence of ORMDL3 and GSDMB also supported this enhancer model

  2. These studies demonstrate that GSDMB, a gene highly linked to asthma but whose function in asthma is previously unknown, regulates AHR and airway remodeling without airway inflammation through a previously unrecognized pathway in which GSDMB induces 5-LO to induce TGF-beta1 in bronchial epithelium.

  3. Full-length GSDMB and its N-terminal domain bind to phosphoinositides or sulfatide, but not cardiolipin. The GSDMB N-terminal domain binds liposomes containing sulfatide, suggesting a role in sulfatide transport. A loop with SNP AAs from controls (Gly299:Pro306) shows high conformational flexibility, but one with AAs (Arg299:Ser306) from people at risk for IBD and asthma is less so and has higher positive surface charge.

  4. Data identifies the ERBB2 co-amplified and co-expressed gene GSDMB as a critical determinant of poor prognosis and therapeutic response in HER2-positive breast cancer.

  5. Chromosome 17q21 genes ORMDL3 and GSDMB are linked to asthma and other immune diseases. (Review)

  6. The rs8067378 SNP variants may increase the expression of GSDMB and the risk of the development and progression of cervical SCC.

  7. GSDMB levels are significantly modulated by NMD. Importantly, both AS isoforms and the identified ecircRNA were significantly dysregulated in peripheral blood mononuclear cells of relapsing-remitting MS patients compared to controls.

  8. We found strong associations among GSDMB polymorphisms and the presence of AERD and FEV1 in Korean patients with asthma. Our findings indicated that genetic variations of GSDMB may be associated with the development of AERD and aspirin-induced bronchospasm.

  9. we investigated the association between GSDMA and GSDMB variants and the incidence of adult and childhood asthma among Jordanians.An association between the GSDMB T/C single nucleotide polymorphism (SNP) genotype and the incidence of childhood asthma was found

  10. childhood asthma is associated with gene polymorphism; meta-analysis

  11. Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation

  12. GSDMB variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.

  13. The GSDMB-driven HSVtk expression vector had a therapeutic effect on the occult peritoneal dissemination model mice.

  14. Gasdermin-B promotes invasion and metastasis in breast cancer cells

  15. Results confirmed the genetic association between GSDMB/ ORMDL3 and childhood asthma and show significant differences in the DNA methylation levels of ORMDL3 promoter of asthmatic children.

  16. 3 SNPs associated with the fraction of exhaled nitric oxide in childhood asthma are rs3751972 in LYRM9; rs944722 in NOS2; and rs8069176 near GSDMB; all at 17q12-q21.

  17. rs11078928 is associated with the production of a novel GSDMB transcript lacking an internal segment

  18. No association between GSDMB polymorphisms and rheumatoid arthritis was observed.

  19. GSDMB SNP rs2305480 (Ser311Pro) was associated with asthma diagnosis (p = 8.9x10-4), bronchial hyperresponsiveness to methacholine (p = 8.2x10-4) and severity (p = 1.5x10-4) with supporting evidence from a second GSDMB SNP rs11078927 (intronic).

  20. GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness.

Gasdermin B (GSDMB) Antigen Profile

Protein Summary

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Gene names and symbols associated with anti-Gasdermin B (GSDMB) Antibodies

  • gasdermin B (GSDMB) antibody
  • GSDML antibody
  • PRO2521 antibody

Protein level used designations for anti-Gasdermin B (GSDMB) Antibodies

gasdermin B , gasdermin-like , gasdermin-B-like , gasdermin-B , gasdermin-like protein

GENE ID SPECIES
509296 Bos taurus
746094 Pan troglodytes
100067983 Equus caballus
100443947 Pongo abelii
100607306 Nomascus leucogenys
55876 Homo sapiens
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