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GSDMB encodes a member of the gasdermin-domain containing protein family. Additionally we are shipping Gasdermin B Proteins (3) and many more products for this protein.
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Data identifies the ERBB2 (show ERBB2 Antibodies) co-amplified and co-expressed gene GSDMB as a critical determinant of poor prognosis and therapeutic response in HER2 (show ERBB2 Antibodies)-positive breast cancer.
Chromosome 17q21 genes ORMDL3 (show ORMDL3 Antibodies) and GSDMB are linked to asthma and other immune diseases. (Review)
The rs8067378 SNP variants may increase the expression of GSDMB and the risk of the development and progression of cervical SCC (show CYP11A1 Antibodies).
GSDMB levels are significantly modulated by NMD. Importantly, both AS isoforms and the identified ecircRNA were significantly dysregulated in peripheral blood mononuclear cells of relapsing-remitting MS patients compared to controls.
We found strong associations among GSDMB polymorphisms and the presence of AERD and FEV1 in Korean patients with asthma. Our findings indicated that genetic variations of GSDMB may be associated with the development of AERD and aspirin-induced bronchospasm.
we investigated the association between GSDMA (show GSDMA Antibodies) and GSDMB variants and the incidence of adult and childhood asthma among Jordanians.An association between the GSDMB T/C single nucleotide polymorphism (SNP) genotype and the incidence of childhood asthma was found
Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation
GSDMB variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.
The GSDMB-driven HSVtk expression vector had a therapeutic effect on the occult peritoneal dissemination model mice.
Gasdermin-B promotes invasion and metastasis in breast cancer cells
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
, gasdermin-like protein