Gasdermin B antibody (N-Term)

Catalog No. ABIN2775462

Cited in 1 publication. The Rabbit Polyclonal anti-Gasdermin B antibody (ABIN2775462) specifically detects Gasdermin B in WB. The antibody is reactive with Human and Horse samples.

Quick Overview for Gasdermin B antibody (N-Term) (ABIN2775462)

Target: Gasdermin B (GSDMB)

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gasdermin B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Gasdermin B Antibody

Binding Specificity: N-Term

Purpose: GSDML Antibody - N-terminal region

Sequence: HLVGEKRTFF GCRHYTTGLT LMDILDTDGD KWLDELDSGL QGQKAEFQIL

Predicted Reactivity: Horse: 100%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GSDML. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSDML

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42519-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Gasdermin B antibody (ABIN2775462)

Adams, Leavitt, Holmes: "Strabismus surgery for internuclear ophthalmoplegia with exotropia in multiple sclerosis." in: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, Vol. 13, Issue 1, pp. 13-5, (2009) (PubMed).

Target Details for Gasdermin B

Target: Gasdermin B (GSDMB)

Alternative Name: GSDML

Background:

Background Information: GSDML belongs to the gasdermin family.GSDML may play a role as secretory or metabolic product involved in secretory pathway. It may also play a role in achieving and maintaining the final differentiation state of epithelial cells.

Gene Name: Gasdermin B

Alternative Symbols: GSDML, PP4052, GSDMB-1, PRO2521

Protein Name: Gasdermin-B

Molecular Weight: 45kDa

Gene ID: 55876

NCBI Accession: NP_061000

UniProt: Q8TAX9