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Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Additionally we are shipping GANAB Proteins (9) and and many more products for this protein.
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progression of neuropathologic and Behavioral abnormalities in a Pompe disease mouse model (6neo/6neo) that displays many features of the human disease
Case Report: GANAB mutation leading to autosomal dominant polycystic kidney disease.
used whole exome sequencing in a discovery cohort of 102 unrelated patients who were excluded for mutations in the 2 most common polycystic liver disease genes, PRKCSH and SEC63, to identify heterozygous loss-of-function mutations in 3 additional genes, ALG8, GANAB, and SEC61B. Similarly to PRKCSH and SEC63, these genes encode proteins that are integral to the protein biogenesis pathway in the endoplasmic reticulum.
Mutations in GANAB gene is associated with Autosomal-Dominant Polycystic Kidney and Liver Disease.
The high frequency of glucosidase II overexpression, which to the best of our knowledge has not been previously described, indicates its crucial roles in lung tumorigenesis and is thus a valuable biomarker
Loss of the tumor suppression function of Hsp60 or GANAB contribute to aggressive cancers.
In males being treated for infertility, neutral alpha-glucosidase activity correlated with the percentage of sperm DNA fragmentation.
the apparent occurrence of an unusual TG 3' splice site in intron 18 is discussed
Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.
alpha glucosidase II alpha subunit
, neutral alpha-glucosidase AB
, glucosidase, alpha; neutral AB
, neutral alpha-glucosidase AB-like
, alpha-glucosidase 2
, carbohydrate processing enzyme of the endoplasmic reticulum
, glucosidase II alpha-subunit
, glucosidase II subunit alpha
, alpha glucosidase 2 alpha neutral subunit
, neutral AB