GANAB antibody (AA 1-260)

Catalog No. ABIN6140952

This Rabbit Polyclonal antibody specifically detects GANAB in WB and IF. It exhibits reactivity toward Human.

Quick Overview for GANAB antibody (AA 1-260) (ABIN6140952)

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANAB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GANAB Antibody

Binding Specificity: AA 1-260

Sequence: MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY KIILTARPFR LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD GAQPEETPRD GDKPEETQGK AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD FSLPGMEHVY GIPEHADNLR LKVTEGGEPY RLYNLDVFQY ELYNPMALYG SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK MMDYLQGSGE TPQTDVRWMS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GANAB

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Alternative Name: GANAB

Background: This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.,GANAB,G2AN,GIIA,GLUII,PKD3,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,GANAB

Molecular Weight: 5 kDa/106 kDa/109 kDa

Gene ID: 23193

UniProt: Q14697