anti-Glycoprotein VI (Platelet) (GP6) Antibodies

GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. Additionally we are shipping GP6 Kits (31) and GP6 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GP6 51206 Q9HCN6
GP6 243816 P0C191
GP6 684555  
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Top anti-GP6 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-GP6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$469.32
Details
Human Rabbit Un-conjugated FACS, WB GP6 Antibody (C-term) (ABIN651878) western blot analysis in K562 cell line lysates (15 µg/lane). This demonstrates the GP6 antibody detected the GP6 protein (arrow). GP6 Antibody (C-term) (ABIN651878) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$469.32
Details
Mouse Rat PE FACS Detection of GPVI in Mouse Platelets by Flow Cytometry. Mouse platelets were stained with Rat Anti-Mouse GPVI PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$351.90
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: GPVI Antibody [NBP1-76941] - A20 lysate with GPVI antibody at 1ug/mL in either the absence or (B) the presence of blocking peptide. Immunohistochemistry-Paraffin: GPVI Antibody [NBP1-76941] - Human heart tissue with Glycoprotein VI antibody at 10 ug/ml. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Mouse Rat Un-conjugated CyTOF, FACS, ICC Detection of GPVI in Mouse platelets by Flow Cytometry. Mouse platelets were stained with Rat Anti-Mouse GPVI Monoclonal Antibody. GPVI in Mouse Platelets. GPVI was detected in immersion fixed adult mouse platelets using Rat Anti-Mouse GPVI Monoclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Anti-Rat IgG Secondary Antibody (red 100 μg Log in to see 8 to 9 Days
$299.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human Jurkat cell lysate; Primary Ab: 1.5µg/ml Rabbit Anti-Human GP6 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15 to 18 Days
$332.00
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot: GPVI Antibody [NBP1-76359] - A-20 lysate with GPVI antibody at 1ug/mL in either the absence or (B) the presence of blocking peptide. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$551.83
Details

GP6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GP6 Antibodies

  1. Mouse (Murine) Monoclonal GP6 Primary Antibody for FACS - ABIN4896696 : Lindsey, Jiang, Woulfe, Papoutsakis: Platelets from mice lacking the aryl hydrocarbon receptor exhibit defective collagen-dependent signaling. in Journal of thrombosis and haemostasis : JTH 2014 (PubMed)

More Antibodies against GP6 Interaction Partners

Human Glycoprotein VI (Platelet) (GP6) interaction partners

  1. This suggests whereas platelet receptor shedding is mainly modulated by calcium-dependent signals, either platelet-surface interactions with the container walls during storage or induced shear stress under long-term agitation, might be also involved in the excessive shedding of GPVI during the storage of PRP (show C4BPA Antibodies)-platelet concentrates.

  2. There was no evidence to suggest that polymorphisms of GP VI T13254C and GP Ibalpha VNTR were associated with CAD (show CAD Antibodies).

  3. Platelet adhesion to collagen induces GPVI dimer clustering. GPVI clustering increases both avidity for collagen and the proximity of GPVI-associated signaling molecules, which may be crucial for the initiation and persistence of signaling

  4. Loss of the platelet surface receptors GPIbalpha (show GP1BA Antibodies) and GPVI in heart failure, CF-VAD (show KCTD1 Antibodies) and ECMO patients may contribute to ablated platelet adhesion/activation, and limit thrombus formation under high/pathologic shear conditions

  5. Novel antithrombotic peptides derived from trowaglerix that acts through GPVI antagonism with greater safety-no severe bleeding.

  6. results support the idea that genetic variability of GP6 regulatory regions can be associated with platelet hyperaggregability - a possible cause of miscarriage

  7. These results demonstrate that GP6 is a receptor for fibrin and provide evidence that this interaction contributes to thrombus growth and stability.

  8. data suggest a novel role for FAK (show PTK2 Antibodies) in GPVI-dependent ROS (show ROS1 Antibodies) formation and platelet activation and elucidate a proximal signaling role for FAK (show PTK2 Antibodies) within the GPVI pathway.

  9. This study identifies GPVI as a platelet receptor for polymerized fibrin with 2 major functions: (1) amplification of thrombin (show F2 Antibodies) generation and (2) recruitment of circulating platelets to clots.

  10. Glaucocalyxin A inhibits platelet activation and thrombus formation preferentially via GPVI signaling pathway.

Mouse (Murine) Glycoprotein VI (Platelet) (GP6) interaction partners

  1. In conclusion, the present study unraveled ceramidase as a crucial player in sphingosine-induced platelet activation following GPVI-dependent signaling.

  2. These results reveal a novel and unexpected function of hepatic Fc-gamma-RIIB in the targeted downregulation of GPVI in vivo.

  3. collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI.

  4. platelet GP6 and thromboxane A2 receptor (show TBXA2R Antibodies) have a role in promoting inflammatory macrophage phenotype in skin inflammation

  5. Novel antithrombotic peptides derived from trowaglerix that acts through GPVI antagonism with greater safety-no severe bleeding.

  6. TULA-2 (show STS1 Antibodies) Protein Phosphatase Suppresses Activation of Syk (show SYK Antibodies) through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr (show TYR Antibodies)(P)346, a Regulatory Site of Syk (show SYK Antibodies).

  7. Inhibition of platelet activation by an anti-GPVI antibody significantly reduces infarct size.

  8. These results demonstrate that GPVI is a receptor for fibrin and provide evidence that this interaction contributes to thrombus growth and stability.

  9. data demonstrate that genetic deletion of GPVI receptor, FcRgamma (show FCER1G Antibodies) chain, or the alpha2beta1 integrin changes the thrombotic potentials of these platelets to collagen dependent on the stimulus mechanism.

  10. data suggest a novel role for FAK (show PTK2 Antibodies) in GPVI-dependent ROS (show ROS1 Antibodies) formation and platelet activation and elucidate a proximal signaling role for FAK (show PTK2 Antibodies) within the GPVI pathway.

GP6 Antigen Profile

Protein Summary

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with GP6

  • glycoprotein VI platelet (GP6) antibody
  • glycoprotein 6 (platelet) (Gp6) antibody
  • glycoprotein VI (Gp6) antibody
  • glycoprotein VI platelet (Gp6) antibody
  • platelet glycoprotein VI (LOC103346235) antibody
  • 9830166G18Rik antibody
  • BDPLT11 antibody
  • Gm469 antibody
  • GP6 antibody
  • GPIV antibody
  • Gpvi antibody

Protein level used designations for GP6

glycoprotein 6 , platelet collagen receptor , platelet glycoprotein VI , glycoprotein VI (platelet) , glycoprotein 5 , glycoprotein 6 (platelet) , glycoprotein VI

GENE ID SPECIES
51206 Homo sapiens
456429 Pan troglodytes
484303 Canis lupus familiaris
243816 Mus musculus
101123066 Ovis aries
684555 Rattus norvegicus
106026629 Cavia porcellus
103346235 Oryctolagus cuniculus
100517829 Sus scrofa
102188249 Capra hircus
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