GP6 antibody (AA 115-265) (Biotin)

Catalog No. ABIN7163594

Product Details anti-GP6 Antibody (Biotin)

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Binding Specificity: AA 115-265

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP6 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Platelet glycoprotein VI protein (115-265AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Alternative Name: GP6 (GP6 Products)

Synonyms: BDPLT11 antibody, GPIV antibody, GPVI antibody, 9830166G18Rik antibody, Gm469 antibody, Gpvi antibody, GP6 antibody, glycoprotein VI platelet antibody, glycoprotein 6 (platelet) antibody, glycoprotein VI antibody, platelet glycoprotein VI antibody, GP6 antibody, Gp6 antibody, LOC103346235 antibody

Background:

Background: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.

Aliases: Glycoprotein 6 antibody, Glycoprotein VI antibody, GP6 antibody, GPIV antibody, GPVI antibody, GPVI_HUMAN antibody, MGC138168 antibody, Platelet collagen receptor antibody, Platelet glycoprotein VI antibody, Platelet glycoprotein VI precursor antibody

UniProt: Q9HCN6