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The protein encoded by HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. Additionally we are shipping HIV-1 Rev Binding Protein Proteins (4) and many more products for this protein.
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Necroptotic RIP1 (show UQCRFS1 Antibodies) phosphorylation and ubiquitination seem to be tightly coordinated: inhibition or absence of RIP1 (show UQCRFS1 Antibodies) kinase activity blocks necroptotic RIP1 (show UQCRFS1 Antibodies) ubiquitination, whereas mutation of RIP1 (show UQCRFS1 Antibodies) necroptosis-associated ubiquitination site (K115R) dampens RIP1 (show UQCRFS1 Antibodies) kinase activity during necroptotic signaling.
HRB knock-down affected CD4 (show CD4 Antibodies) downregulation induced by Nef but not by HIV-1 Vpu.
Selenite caused CYLD (show CYLD Antibodies) upregulation via LEF1 (show LEF1 Antibodies) and cIAP downregulation, both of which contribute to the degradation of ubiquitin chains on RIP1 (show UQCRFS1 Antibodies) and subsequent caspase-8 (show CASP8 Antibodies) activation and colorectal tumor cell apoptosis.
The top primary GWAS association of Airway hyperresponsiveness was in rs6731443 (P-value 2.5E-06) located within the AGFG1 genes.
Association ofalpha-synuclein with Rab attachment receptor protein and soluble sensitive factor attachment receptors (SNAREs) highlights a key role for membrane transport defects in alpha-synuclein-mediated pathology.
The authors show that cells lacking functional HRB have significantly reduced production of influenza virus progeny and that this defect results from impaired viral ribonucleoprotein (vRNP) delivery to the plasma membrane.
hRIP is an essential cellular Rev cofactor, which acts at a previously unanticipated step in HIV-1 RNA export.
Study demonstrates that the clathrin-mediated endocytosis of the SNARE VAMP7 is directly mediated by Hrb, a clathrin adaptor and ArfGAP.
HRB is involved in clathrin-dependent endocytosis and recruits TI-VAMP (show VAMP7 Antibodies) in this process
Lack of an acrosome in Hrb mutant spermatids does not prevent the development of the acroplaxome. In the Hrb mutant, myosin-Va (show MYO5A Antibodies)-bound proacrosome vesicles tether to the acroplaxome, where they flatten and form a flat sac (show ADCY10 Antibodies), designated pseudoacrosome.
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
ArfGAP with FG repeats 1
, HIV-1 Rev binding protein
, arf-GAP domain and FG repeats-containing protein 1
, nucleoporin-like protein RIP
, hiv-1 rev binding protein
, HIV-1 Rev-binding protein
, Rab, Rev/Rex activation domain-binding protein
, arf-GAP domain and FG repeat-containing protein 1
, hRIP, Rev interacting protein
, rev-interacting protein
, rev/Rex activation domain-binding protein
, HIV-1 Rev-binding protein homolog