anti-Histone Cluster 1, H3a (HIST1H3A) Antibodies

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Additionally we are shipping Histone Cluster 1, H3a Kits (1) and Histone Cluster 1, H3a Proteins (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HIST1H3A 8350 P68431
HIST1H3A 360198 P68433
HIST1H3A    
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Top anti-Histone Cluster 1, H3a Antibodies at antibodies-online.com

Showing 10 out of 226 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: Rabbit Target Name: HIST1H3A Sample Type: Human 721_B Antibody Dilution: 1.0ug/ml  HIST1H3A is supported by BioGPS gene expression data to be expressed in 721_B WB Suggested Anti-HIST1H3A Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of extract from HeLa cells using Histone H3.1 Antibody (S10) (ABIN658963, Lane 1 and 2) and Phospho-Histone H3.1-S10 Antibody (ABIN658964, Lane 3 and 4). Dilution: 1:500~1:1000 Immunofluorescence staining of methanol-fixed HeLa cells using Histone H3.1 Antibody (S10) (ABIN658963, Red). Dilution: 1:100~200 0.1 mg Log in to see 10 to 11 Days
$475.29
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extract from HeLa cells using Histone H3.1 Antibody (S10) (ABIN658963, Lane 1 and 2) and Phospho-Histone H3.1-S10 Antibody (ABIN658964, Lane 3 and 4). Dilution: 1:500~1:1000 Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-Histone H3.1-S10 Antibody (ABIN658964)(left) or the same antibody preincubated with blocking peptide(right). Dilution: 1:50~1:100 0.1 mg Log in to see 10 to 11 Days
$475.29
Details
Human Rabbit Un-conjugated DB, ICC, IF, WB Western Blot: HIST1H3A Antibody [NBP2-16837] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 15% SDS PAGE gel, diluted at 1:10000. Western Blot: HIST1H3A Antibody [NBP2-16837] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 15% SDS PAGE gel, diluted at 1:10000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Mouse Un-conjugated IHC (p), WB Immunohistochemistry: HIST1H3A Antibody (CL4967)  - Immunohistochemical staining of human cerebellum shows strong nuclear immunoreactivity in neuronal and glial cells. Immunohistochemistry: HIST1H3A Antibody (CL4967)  - Immunohistochemical staining of human kidney shows strong nuclear positivity in renal tubules cells. 100 μL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated ChIP, IF, WB Western Blot (Cell lysate) analysis of (1) 25 ug whole cell extracts of HeLa cells, (2) 1 ug of recombinant histone H2A, (3) 1 ug of recombinant histone H2B, (4) 1 ug of recombinant histone H3, and (5) 1 ug of recombinant histone H4. Western Blot analysis of (1) 30 ug whole cell extracts of HeLa cells, (2) 30 ug whole cell extracts of K562 cells, (3) 30 ug whole cell extracts of MCF7 cells, (4) 30 ug whole cell extracts of U2OS cells, (5) 30 ug whole cell extracts of HepG2 cells, (6) 30 ug whole cell extracts of Jurkat cells, (7) 30 ug whole cell extracts of NIH3T3 cells, (8) 30 ug whole cell extracts of E14Tg2a mouse ES cells. 50 μg Log in to see 11 to 12 Days
$517.50
Details
Human Mouse Un-conjugated ChIPSeq, ChIP, ELISA, IF, WB ChIP assays were performed using human HeLa cells. A titration consisting of 1, 2, 5 and 10 ug of antibody per ChIP experiment was analyzed. IgG (2 ug/IP) was used as a negative IP control. Quantitative PCR was performed with primers specific for the promoter of the constitutively expressed GAPDH and c-fos genes, used as positive controls, and for exon 2 of the inactive myoglobin (MB) gene and the Sat2 satellite repeat, used as negative controls. The figure shows the recovery, expressed as a % of input (the relative amount of immunoprecipitated DNA compared to input DNA after qPCR analysis). These results are in accordance with the observation that trimethylation of K4 at histone H3 is associated with the promoters of active genes. ChIP was performed on sheared chromatin from 1 million HeLaS3 cells using antibody. The figure shows the peak distribution along two 5 Mb regions of chromosome 3 and 5 and in two 100 kb regions surrounding the GAPDH and c-fos positive control genes. These results clearly show an enrichment of the H3K4 trimethylation at the promoters of active genes. 50 μg Log in to see 11 to 12 Days
$648.60
Details
Human Mouse Un-conjugated ChIP, ELISA, IF, WB ELISA is a quantitative method used to determine the titer of the antibody using a serial dilution of antibody against Histone H3 (K9me2). The wells were coated with peptides containing the unmodified H3K9 as well as the monomethylated, dimethylated and trimethylated H3K9 and the dimethylated H3K4 and H3K27. The figure shows a high specificity of the antibody for the modification of interest. Western Blot (Cell lysate) analysis of 15 ug histone extracts of HeLa cells. 50 μg Log in to see 11 to 12 Days
$648.60
Details
Human Mouse Un-conjugated ChIP, ELISA, IF, WB Immunofluorescent staining of Hela cell line with antibody followed by an anti-mouse antibody conjugated to Alexa594 (left). The middle panel shows staining of the nuclei with DAPI. A merge of the two stainings (right). ChIP assays were performed using HeLa cells. A titration of the antibody consisting of 1, 5 and 10 ug per ChIP experiment was analysed. IgG (5 ug/IP) was used as negative IP control. QPCR was performed with primers for the promoter and the coding region of the GAPDH gene, and for the RPL10 and HBB promoters. The figure shows the recovery, expressed as a % of input (the relative amount of immunoprecipitated DNA compared to input DNA after qPCR analysis). 50 μg Log in to see 11 to 12 Days
$648.60
Details
Human Mouse Un-conjugated ChIP, ELISA, IF, WB ChIP assays were performed using HeLa cells. A titration of the antibody consisting of 1, 5 and 10 ug per ChIP experiment was analysed. IgG (5 ug/IP) was used as negative IP control. QPCR was performed with primers for the GAPDH promoter and for exon 2 of the myoglobin gene. The figure shows the recovery, expressed as a % of input (the relative amount of immunoprecipitated DNA compared to input DNA after qPCR analysis). Western Blot (Cell lysate) analysis of 15 ug histone extracts of HeLa cells. 50 μg Log in to see 11 to 12 Days
$648.60
Details

More Antibodies against Histone Cluster 1, H3a Interaction Partners

Human Histone Cluster 1, H3a (HIST1H3A) interaction partners

  1. Here, we report that JMJD5, a Jumonji C (JmjC) domain-containing protein, is a Cathepsin L-type protease that mediates histone H3 N-tail proteolytic cleavage under stress conditions that cause a DNA damage response.

  2. Data suggest that Ki-67 (show MKI67 Antibodies) antigen proliferative index has important limitations and hhosphohistone H3 (PHH3) is an alternative proliferative marker.

  3. This data indicates that, in the early developing human brain, HIST1H3B constitutes the largest proportion of H3.1 transcripts among H3.1 isoforms.

  4. This series of 47 diffuse midline gliomas, histone H3 (show HIST3H3 Antibodies)-K27M mutation was mutually exclusive with IDH1 (show IDH1 Antibodies)-R132H mutation and EGFR (show EGFR Antibodies) amplification, rarely co-occurred with BRAF (show BRAF Antibodies)-V600E mutation, and was commonly associated with p53 (show TP53 Antibodies) overexpression, ATRX (show ATRX Antibodies) loss, and monosomy 10. Among these K27M+ diffuse midline gliomas.

  5. Data show that histone chaperone HIRA (show HIRA Antibodies) co-localizes with viral genomes, binds to incoming viral and deposits histone H3.3 (show H3F3A Antibodies) onto these.

  6. These experiments showed that PHF13 (show PHF13 Antibodies) binds specifically to DNA and to two types of histone H3 (show HIST3H3 Antibodies) methyl tags (lysine 4-tri (show VANGL2 Antibodies)-methyl or lysine 4-di-methyl) where it functions as a transcriptional co-regulator.

  7. Hemi-methylated CpGs DNA recognition activates UHRF1 (show UHRF1 Antibodies) ubiquitylation towards multiple lysines on the H3 tail adjacent to the UHRF1 (show UHRF1 Antibodies) histone-binding site.

  8. We describe, for the first time, the MR imaging features of pediatric diffuse midline gliomas with histone H3 (show HIST3H3 Antibodies) K27M mutation

  9. Approximately 30% of pediatric high grade gliomas (pedHGG) including GBM and DIPG harbor a lysine 27 mutation (K27M) in histone 3.3 (H3.3) which is correlated with poor outcome and was shown to influence EZH2 (show EZH2 Antibodies) function.

  10. H3F3A (show H3F3A Antibodies) K27M mutation in adult cerebellar HGG is not rare.

Mouse (Murine) Histone Cluster 1, H3a (HIST1H3A) interaction partners

  1. Hemi-methylated DNA opens a closed conformation of UHRF1 (show UHRF1 Antibodies) to facilitate its H3 histone (show HIST1H3B Antibodies) recognition.

  2. Findings show that CCL2 (show CCL2 Antibodies) and CCL3 (show CCL3 Antibodies) are upregulated in the injured peripheral nerve through epigenetic histone modification in infiltrating immune cells such as macrophages.

  3. This result suggests that the incorporation of H3.1 has a detrimental effect on the process of genome remodeling and contributes to the low success rate of somatic nuclear cloning.

Histone Cluster 1, H3a (HIST1H3A) Antigen Profile

Protein Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails\; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Gene names and symbols associated with HIST1H3A

  • histone cluster 1 H3 family member a (HIST1H3A) antibody
  • histone cluster 1, H3a (Hist1h3a) antibody
  • H3/A antibody
  • H3FA antibody

Protein level used designations for HIST1H3A

H3 histone family, member A , histone 1, H3a , histone H3.1 , histone H3/a

GENE ID SPECIES
8350 Homo sapiens
360198 Mus musculus
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