anti-Immunoglobulin Superfamily, Member 8 (IGSF8) Antibodies

IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Additionally we are shipping IGSF8 Proteins (13) and IGSF8 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGSF8 93185 Q969P0
IGSF8 140559 Q8R366
IGSF8 304979  
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Top anti-IGSF8 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-IGSF8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate WB Suggested Anti-IGSF8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IF, WB 100 μL Log in to see 9 to 11 Days
$494.62
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD316 expression in K562 (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB IGSF8 Antibody (Center) (ABIN656323) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. Anti-IGSF8 Antibody (Center) at 1:1000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 65 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:1000 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded (FFPE) human kidney tissue using CD316 / IGSF8 Antibody , followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IGSF8 antibody for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in mouse cerebellum tissue lysates (35ug/lane) using Cd316 / IGSF8 Antibody . This demonstrates the IGSF8 antibody detected the IGSF8 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Mouse Goat Un-conjugated CyTOF, FACS, ICC, WB Detection of IGSF8/CD316 in Neuro-2A Mouse Cell Line by Flow Cytometry. Neuro-2A mouse neuroblastoma cell line was stained with Goat Anti-Mouse IGSF8/CD316 Antigen Affinity-purified Polyclonal Antibody. IGSF8/CD316 in Neuro-2A Mouse Cell Line. IGSF8/CD316 was detected in immersion fixed Neuro-2A mouse neuroblastoma cell line using Goat Anti-Mouse IGSF8/CD316 Antigen Affinity-purified Polyclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Anti-Goat IgG Secondary Antibody (red 100 μg Log in to see 8 to 9 Days
$300.58
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see Available
$181.73
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-IGSF8 antibody  ABIN960784 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-IGSF8 antibody  ABIN960784 IHC staining of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Kidney, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Mouse Goat Biotin FACS, ICC, WB IGSF8/CD316 in Neuro-2A Mouse Cell Line. IGSF8/CD316 was detected in immersion fixed Neuro-2A mouse neuroblastoma cell line using Goat Anti-Mouse IGSF8/CD316 Biotinylated Antigen Affinity-purified Polyclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Streptavidin (red 50 μg Log in to see 8 to 9 Days
$323.18
Details

Top referenced anti-IGSF8 Antibodies

  1. Mouse (Murine) Polyclonal IGSF8 Primary Antibody for CyTOF, FACS - ABIN4899918 : Bye, Jönsson, Björklund, Parish, Thompson: Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)
    Show all 3 Pubmed References

More Antibodies against IGSF8 Interaction Partners

Human Immunoglobulin Superfamily, Member 8 (IGSF8) interaction partners

  1. EWI-2 negatively regulates TGF-beta signaling and its downstream events including cytostasis (in vitro and in vivo), EMT-like changes, cell migration, CD271-dependent invasion, and lung metastasis (in vivo).

  2. Authors demonstrated that EWI-2wint promotes CD81 clustering and confinement in CD81-enriched areas.

  3. The EWI-2/alpha-actinin complex is involved in regulation of the actin cytoskeleton at T cell immune and virological synapses, providing a link between membrane microdomains and the formation of polarized membrane structures involved in T cell recognition.

  4. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  5. analysis of interacting regions of CD81 and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection

  6. EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells.

  7. EWI-2-dependent reorganization of alpha4beta1-CD81 complexes on the cell surface is responsible for EWI-2 effects on integrin-dependent morphology and motility functions

  8. EWI proteins EWI-2 and EWI-F, alpha3beta1 and alpha6beta4 integrins, and protein palmitoylation have contrasting effects on cell surface CD9 organization

  9. EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins

  10. Important functions of recently activated dendritic cells are thus critically modulated by the newly discovered HSPA8-EWI-2 interaction.

  11. CD81 partner EWI-2wint inhibits hepatitis C virus entry [EWI-2wint]

  12. EWI-2 causes a substantial molecular reorganization of multiple molecules known to affect proliferation and/or invasion of astrocytes and/or glioblastomas.

Mouse (Murine) Immunoglobulin Superfamily, Member 8 (IGSF8) interaction partners

  1. IgSF8 is present in developing olfactory sensory neuron synapses, and it interacts with Tspan CD9.

  2. Igsf8-deficient eggs retain the normal level and localization of CD9, resulting in normal microvilli formation indicating that IGSF8 is dispensable in fertility.

  3. This study showed that the EWI2 cytoplasmic tail actively engages with the cell membrane via phosphatidylinositol phosphate binding and palmitoylation.

  4. Igsf8 is first expressed at E9.5 in a ventral domain of the neural tube, with dorsal expression apparent at E10.5.. From E11.5, Igsf8 occurs at the edge of the ventricular zone, in postmitotic neuroblasts, and in sensory ganglia.

  5. EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins

  6. Report that the expression level of EWI-2 on the Cd9(-/-) oocyte surface is <10% of the wild-type level. Hence, the severe reduction in EWI-2 activity may be responsible for the loss of fusion ability.

  7. Immunoglobulin superfamily member IgSF8 (EWI-2) and CD9 in fertilisation: evidence of distinct functions for CD9 and a CD9-associated protein in mammalian sperm-egg interaction.

IGSF8 Antigen Profile

Protein Summary

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with IGSF8

  • immunoglobulin superfamily, member 8 (igsf8) antibody
  • immunoglobulin superfamily member 8 (IGSF8) antibody
  • immunoglobulin superfamily, member 8 (Igsf8) antibody
  • AA033172 antibody
  • AU041109 antibody
  • CD81P3 antibody
  • CD316 antibody
  • ESTM34 antibody
  • EWI-2 antibody
  • EWI2 antibody
  • IGSF8 antibody
  • KCT-4 antibody
  • LIR-D1 antibody
  • MGC77222 antibody
  • MGC151661 antibody
  • PGRL antibody
  • R75384 antibody

Protein level used designations for IGSF8

immunoglobulin superfamily member 8 , immunoglobulin superfamily, member 8 , immunoglobulin superfamily member 8-like , CD81 partner 3 , glu-Trp-Ile EWI motif-containing protein 2 , keratinocytes-associated transmembrane protein 4 , prostaglandin regulatory-like protein , PG regulatory-like protein , keratinocyte-associated transmembrane protein 4

GENE ID SPECIES
404631 Danio rerio
469549 Pan troglodytes
519266 Bos taurus
100058209 Equus caballus
100154024 Sus scrofa
100338663 Oryctolagus cuniculus
100441861 Pongo abelii
100595459 Nomascus leucogenys
93185 Homo sapiens
140559 Mus musculus
304979 Rattus norvegicus
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