Inosine Triphosphatase (ITPA) ELISA Kits

ITPA encodes an inosine triphosphate pyrophosphohydrolase. Additionally we are shipping Inosine Triphosphatase Antibodies (88) and Inosine Triphosphatase Proteins (24) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ITPA 16434 Q9D892
ITPA 311422 D3ZW55
ITPA 3704 Q9BY32
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Top Inosine Triphosphatase ELISA Kits at antibodies-online.com

Showing 5 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.049 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$757.89
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Human 0.469 ng/mL 0.78 ng/mL - 50 ng/mL A typical standard curve 96 Tests Log in to see 13 to 16 Days
$641.23
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Rat
  96 Tests Log in to see 15 to 18 Days
$875.60
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Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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Chicken
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$1,095.60
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More ELISA Kits for Inosine Triphosphatase Interaction Partners

Mouse (Murine) Inosine Triphosphatase (ITPA) interaction partners

  1. The authors analysed ITPA-deficient human and mouse cells, and revealed that ITPA deficiency induces MLH1/PMS2- and p53-dependent growth arrest and DNA instability in mammalian cells.

  2. In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.

  3. The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP

Human Inosine Triphosphatase (ITPA) interaction partners

  1. Thiopurine methyltransferase (TPMT) and inosine triphosphatase (ITPA) genotypes significantly influence the metabolism of 6-mercaptopurine (6MP).

  2. Inosine triphosphate pyrophosphatase dephosphorylates ribavirin triphosphate, and reduced enzymatic activity potentiates mutagenesis in hepatitis C virus.

  3. This study suggests that the polymorphisms in the ITPA gene influence the severity of anaemia during the first month of a DAA/RBV-based treatment in HCV-related cirrhosis.

  4. baseline testing of this single ITPA SNP might help to identify the subset of patients with the greatest risk for experiencing RBV-induced anaemia, which may be particularly helpful in those with underlying cardiovascular disease. In such patients, RBV-sparing regimens should be preferred.

  5. The authors analysed ITPA-deficient human and mouse cells, and revealed that ITPA deficiency induces MLH1/PMS2- and p53-dependent growth arrest and DNA instability in mammalian cells.

  6. ITPA variant rs1127354C>A significantly predict RBV-induced anaemia during the first 3 months of treatment and it is recommended to be assessed before RBV administration

  7. The ITPA gene polymorphism rs1127354 heterozygous genotype (CA) may influence Hemoglobin levels and protect against hemolytic anemia during ribavirin containing regimens for hepatitis C

  8. Four gene signature (PTEN, PIK3C2A, ITPA and BCL3) is an independent prognostic factors of both overall survival and disease-free survival in clear-cell renal-cell carcinoma.

  9. Inosine triphosphatase polymorphism appeared to correlate with anemia in- cidence and RBV dose reduction during SOF/RBV therapy.

  10. Inosine triphosphatase (IPTA) rs1127354 variants but not rs7270101 were found in Chinese patients infected with chronic hepatitis C. IPTA rs1127354 variants and related ITPase were not only related with ribavirin-induced hemolytic anemia but also directly affected the virological response to pegylated interferon plus ribavirin combination therapy in Chinese chronic hepatitis C virus-infected patients.

  11. This study concluded that HIV-infection seems to be interfering with the nucleotide metabolism in leukocytes, including CD4 lymphocytes, by decreasing ITPase expression, independently of ITPA genotype.

  12. A high prevalence of the ITPA polymorphisms associated with ribavirin-induced hemolytic anemia was found in Mexican Native Amerindians.

  13. ITPA gene is associated with protection of anemia in patients with chronic hepatitis during antiviral therapy.

  14. We concluded that ITPase activity plays an important function and that ATP concentration changes due to therapy are related to the Hb decreasing mechanism in the early period of therapy with HCV treatment

  15. The aim of the study was to investigate frequencies of TPMT and ITPA polymorphisms in Lithuanian inflammatory bowel disease patients and analyze their association with azathioprine-related adverse events.

  16. ITPA polymorphism was associated with RBV-induced anemia and thrombocytopenia in Egyptian patients with hepatitis C virus genotype 4 infection.

  17. Hyperbilirubinemia develops at early time points after simeprevir administration in most cases and is dependent on the ITPA genotype.

  18. Genetic variants in inosine triphosphatase (ITPA) gene have been linked to the haemolytic anaemia induced by peg-interferon and ribavirin treatment.

  19. polymorphisms increase the likelihood of developing hemolytic anemia for HCV-infected patients on RBV-based therapy, particularly rs1127354 CC and rs7270101 AA genotypes [meta-analysis]

  20. The association of IL28B and APOH single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA SNPs with anemia related phenotypes.

Inosine Triphosphatase (ITPA) Antigen Profile

Antigen Summary

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ITPA

  • inosine triphosphatase (itpa) antibody
  • inosine triphosphatase (ITPA) antibody
  • inosine triphosphatase (LOC733043) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa) antibody
  • inosine triphosphatase (Itpa) antibody
  • Inosine triphosphate pyrophosphatase (pco148511) antibody
  • inosine triphosphatase S homeolog (itpa.S) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (itpa) antibody
  • 2010016I08Rik antibody
  • AU020102 antibody
  • C20orf37 antibody
  • DDBDRAFT_0215619 antibody
  • DDBDRAFT_0238062 antibody
  • DDB_0215619 antibody
  • DDB_0238062 antibody
  • dJ794I6.3 antibody
  • HLC14-06-P antibody
  • Itp antibody
  • ITPase antibody
  • NTPase antibody
  • si:ch73-18j6.1 antibody
  • si:dkey-19f21.1 antibody

Protein level used designations for ITPA

inosine triphosphate pyrophosphatase , inosine triphosphatase , ITPase , NTPase , non-canonical purine NTP pyrophosphatase , non-standard purine NTP pyrophosphatase , nucleoside triphosphate pyrophosphatase , nucleoside-triphosphate diphosphatase , nucleoside-triphosphate pyrophosphatase , inosine triphosphatase-A , inosine triphosphate pyrophosphohydrolase , putative oncogene protein HLC14-06-P , inosine triphosphatase A , Inosine triphosphatase , Non-canonical purine NTP pyrophosphatase , Non-standard purine NTP pyrophosphatase , Nucleoside-triphosphate diphosphatase , Nucleoside-triphosphate pyrophosphatase , PCO148511_ov , hypothetical protein , pco148511(169)

GENE ID SPECIES
8625642 Dictyostelium discoideum AX4
100345066 Oryctolagus cuniculus
733043 Bombyx mori
100157088 Sus scrofa
16434 Mus musculus
311422 Rattus norvegicus
3704 Homo sapiens
613653 Bos taurus
100283993 Zea mays
424390 Gallus gallus
735008 Xenopus laevis
557834 Danio rerio
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