Inositol-Trisphosphate 3-Kinase A (ITPKA) ELISA Kits

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. Additionally we are shipping ITPKA Antibodies (66) and ITPKA Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ITPKA 228550 Q8R071
ITPKA 3706 P23677
ITPKA 81677 P17105
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Top ITPKA ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Human
  96 Tests 2 to 3 Days
$380.00
Details

More ELISA Kits for ITPKA Interaction Partners

Mouse (Murine) Inositol-Trisphosphate 3-Kinase A (ITPKA) interaction partners

  1. Thisstudy shows that overexpressed IP3-kinase A plays a role in some forms of hippocampus-dependent learning and memory tasks as well as in synaptic transmission and plasticity by regulating both presynaptic and postsynaptic functions.

  2. Findings demonstrate that IP3K-A plays an important role in regulating affective states by modulating metabotropic receptor signaling pathways and neural activity in the amygdala.

  3. At synapses of Inositol-1,4,5-trisphosphate 3-kinase-A deficient neurons the levels of Ins(1,4,5)P3-5-phosphatase (inpp5a) and sarcoplasmic/endoplasmic reticulum calcium ATPase pump-2b (serca2b) were increased.

  4. Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.

  5. These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6, at least in mouse embryonic fibroblasts.[Itpka, Itpkb, Itpkc]

  6. Inositol 1,4,5-trisphosphate 3-kinase A is critical for spatial and temporal regulation of spine actin remodeling, synaptic plasticity, and learning and memory via an activity-dependent Rac scaffolding mechanism.

Human Inositol-Trisphosphate 3-Kinase A (ITPKA) interaction partners

  1. IP3K-A binds to EB3 and their binding affinity is precisely regulated by protein kinase A (PKA)-dependent phosphorylation of IP3K-A at Ser119 (pSer119). The complex of IP3K-A and EB3 dissociates and reassociates rapidly during chemically induced LTP.

  2. ITPKA is a potential oncogene that it is overexpressed in most tumors, and its overexpression promotes tumorigenesis; ITPKA gene body methylation regulates its expression and serves as a novel and potential biomarker for early cancer detection

  3. Our data indicated that ITPKA expression was significantly up-regulated in hepatocellular carcinoma and could serve as a potential novel prognostic biomarker

  4. describe the crystal structure of the complex between human Ca2+/CaM and the CaM-binding region of human IP3-3K isoform A (residues 158-183)

  5. we conclude that the observed expression of ITPKA early in tumor development increases the metastatic potential of lung adenocarcinoma cells.

  6. Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.

  7. results highlight the potential role of the three isoforms of InsP3 3-kinase as direct InsP3 metabolizing enzymes and direct regulators of Ca2+ responses to extracellular signals

  8. We report the structure of an IPK, the human Ins(1,4,5)P3 3-kinase-A, both free and in complexes with substrates and products.

  9. Data suggest that ITPKA may be related to carcinogenesis by the modulation of inositol polyphosphates and Ca2+ homeostasis and that ITPKA may be a potential novel molecular target and biomarker.

  10. the morphological changes induced by IP3K-A are mediated by non-enzymatic activities of the protein.

ITPKA Antigen Profile

Antigen Summary

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

Gene names and symbols associated with ITPKA

  • inositol-trisphosphate 3-kinase A-like (LOC564528) antibody
  • Inositol-trisphosphate 3-kinase A (ip3ka) antibody
  • inositol-trisphosphate 3-kinase A (ITPKA) antibody
  • inositol 1,4,5-trisphosphate 3-kinase A (Itpka) antibody
  • inositol-trisphosphate 3-kinase A (Itpka) antibody
  • IP3-3KA antibody
  • IP3KA antibody

Protein level used designations for ITPKA

1D-myo-inositol-trisphosphate 3-kinase A , Inositol-trisphosphate 3-kinase A , IP3 3-kinase A , IP3-kinase A , IP3K A , inositol-trisphosphate 3-kinase A , insP 3-kinase A , inositol 1,4,5-trisphosphate 3-kinase A , inositol 1,4,5-triphosphate 3-kinase , inositol 145-triphosphate 3-kinase

GENE ID SPECIES
564528 Danio rerio
100196437 Salmo salar
100343586 Oryctolagus cuniculus
228550 Mus musculus
3706 Homo sapiens
81677 Rattus norvegicus
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