anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) Antibodies

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Additionally we are shipping ITGAE Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGAE 16407 Q60677
ITGAE 83577  
ITGAE 3682 P38570
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Top anti-ITGAE Antibodies at antibodies-online.com

Showing 10 out of 350 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse FITC FACS, IHC (f), IP, WB Surface staining of CD103 on PHA-activated PBMC with anti-CD103 (Ber-ACT8) FITC. 100 Tests Log in to see 5 to 7 Days
$316.25
Details
Human Mouse PE FACS, IHC (f), IP, WB Surface staining of CD103 on PHA-activated PBMC with anti-CD103 (Ber-ACT8) PE. 100 Tests Log in to see 5 to 7 Days
$366.85
Details
Mouse Rat Biotin FACS   0.1 mg Log in to see 15 to 18 Days
$244.43
Details
Human Mouse Un-conjugated FACS, IHC (f), IP, WB   0.1 mg Log in to see 5 to 7 Days
$253.00
Details
Human Mouse APC IHC (f), FACS, IP, WB Surface staining of CD103 on human peripheral blood cells with anti-CD103 (Ber-ACT8) APC. 100 Tests Log in to see 5 to 7 Days
$366.85
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD103 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IHC (fro), FACS, IP, WB   0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CD103 Antibody (C-term) in K562 cell line lysates (35ug/lane). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Hamster Biotin FACS 200 μg Log in to see 10 to 12 Days
$208.36
Details
Mouse Hamster PE FACS 100 μg Log in to see 10 to 12 Days
$214.30
Details

Top referenced anti-ITGAE Antibodies

  1. Mouse (Murine) Monoclonal ITGAE Primary Antibody for FACS - ABIN2688874 : Andrew, Rott, Kilshaw, Butcher: Distribution of alpha 4 beta 7 and alpha E beta 7 integrins on thymocytes, intestinal epithelial lymphocytes and peripheral lymphocytes. in European journal of immunology 1996 (PubMed)
    Show all 10 Pubmed References

  2. Mouse (Murine) Monoclonal ITGAE Primary Antibody for BR, IHC (fro) - ABIN1176991 : Feng, Wang, Yuan, Parker, Farber, Hadley: CD103 expression is required for destruction of pancreatic islet allografts by CD8(+) T cells. in The Journal of experimental medicine 2002 (PubMed)
    Show all 10 Pubmed References

  3. Human Monoclonal ITGAE Primary Antibody for FACS, IHC (f) - ABIN810076 : Jaensson, Uronen-Hansson, Pabst, Eksteen, Tian, Coombes, Berg, Davidsson, Powrie, Johansson-Lindbom, Agace: Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. in The Journal of experimental medicine 2008 (PubMed)
    Show all 9 Pubmed References

  4. Human Monoclonal ITGAE Primary Antibody for FACS, IHC (f) - ABIN810081 : Zhang, Bertucci, Ramsey-Goldman, Burt, Datta et al.: Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of ... in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 9 Pubmed References

  5. Human Monoclonal ITGAE Primary Antibody for FACS, IHC (f) - ABIN968934 : Poles, Barsoum, Yu, Yu, Sun, Daly, He, Mehandru, Talal, Markowitz, Hurley, Ho, Zhang: Human immunodeficiency virus type 1 induces persistent changes in mucosal and blood gammadelta T cells despite suppressive therapy. in Journal of virology 2003 (PubMed)
    Show all 9 Pubmed References

  6. Human Monoclonal ITGAE Primary Antibody for IHC (f), FACS - ABIN2749099 : León, Roy: Isolation of human small bowel intraepithelial lymphocytes by annexin V-coated magnetic beads. in Laboratory investigation; a journal of technical methods and pathology 2004 (PubMed)
    Show all 7 Pubmed References

  7. Human Monoclonal ITGAE Primary Antibody for FACS, IF - ABIN2688873 : DiGiuseppe, Borowitz: Clinical utility of flow cytometry in the chronic lymphoid leukemias. in Seminars in oncology 1998 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal ITGAE Primary Antibody for IHC (fro), FACS - ABIN2478026 : Falini, Pileri, Flenghi, Liberati, Stein, Gerli, Minelli, Martelli, Lauria, Poggi: Selection of a panel of monoclonal antibodies for monitoring residual disease in peripheral blood and bone marrow of interferon-treated hairy cell leukaemia patients. in British journal of haematology 1991 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal ITGAE Primary Antibody for IHC (fro), FACS - ABIN2478020 : Flenghi, Spinozzi, Stein, Krushwitz, Pileri, Falini: LF61: a new monoclonal antibody directed against a trimeric molecule (150 kDa, 125 kDa, 105 kDa) associated with hairy cell leukaemia. in British journal of haematology 1991 (PubMed)
    Show all 3 Pubmed References

  10. Cynomolgus Monoclonal ITGAE Primary Antibody for IHC (fro), FACS - ABIN2478022 : Cerf-Bensussan, Guy-Grand, Lisowska-Grospierre, Griscelli, Bhan: A monoclonal antibody specific for rat intestinal lymphocytes. in Journal of immunology (Baltimore, Md. : 1950) 1986 (PubMed)
    Show all 4 Pubmed References

More Antibodies against ITGAE Interaction Partners

Mouse (Murine) Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) interaction partners

  1. The adoptive transfer of CD103(+) cDC1s to Batf3 (show BATF3 Antibodies) deficient animals reversed these observed changes and more importantly could attenuate cellular damage and inflammation in established steatohepatitis.

  2. AEbeta7 is of key relevance for gut trafficking of inflammatory bowel disease (IBD) CD8(+) T cells and CD4(+) Th9 cells in vivo and mainly retention might account for this effect. These findings indicate that blockade of alphaEbeta7 in addition to alpha4beta7 may be particularly effective in intestinal disorders with expansion of CD8(+) and Th9 cells such as IBD.

  3. Mesenteric lymph node CD11b (show ITGAM Antibodies)(-) CD103(+) PD-L1 (show CD274 Antibodies)(High) dendritic cell subset probably takes up luminal antigens in the intestine, migrates to MLNs, and highly induces regulatory T cells through TGF-beta (show TGFB1 Antibodies) activation.

  4. NR4A3 (show NR4A3 Antibodies) plays an important role in the regulation of CD103+ mDCs by regulating CCR7 (show CCR7 Antibodies)-dependent cell migration.

  5. Oral treatment with the mucosal adjuvant cholera toxin (CT) induces expression of T cell immunoglobulin and mucin domain containing 4 (TIM-4 (show TIMD4 Antibodies)) on a proportion of CD103+ CD11b (show ITGAM Antibodies)+ dendritic cell (DC) in the intestinal lamina propria (LP).

  6. while alphaE (CD103) expression is indeed associated with hTGFbeta1 in vivo, it has little, if any, influence on the course of the psoriasis-like phenotype in K5.hTGFbeta1 transgenic mice

  7. Intestinal CD103(+)CD11b (show ITGAM Antibodies)(-) dendritic cells restrain colitis via IFN-gamma-induced (show SAMHD1 Antibodies) anti-inflammatory response in epithelial cells.

  8. Antigen-specific cytotoxic T lymphocytes target airway CD103+ and CD11b (show ITGAM Antibodies)+ dendritic cells to suppress allergic inflammation.

  9. CD103 on FoxP3 (show FOXP3 Antibodies)+ Treg cells was involved in Treg retention to inflamed skin.

  10. Interleukin-12-producing CD103+ CD11b (show ITGAM Antibodies)- CD8 (show CD8A Antibodies)+ dendritic cells are responsible for eliciting gut (show GUSB Antibodies) intraepithelial lymphocyte response against Encephalitozoon cuniculi.

Human Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) interaction partners

  1. Pxn (show PXN Antibodies) binding to the CD103 cytoplasmic tail triggers alphaEbeta7 integrin outside-in signaling that promotes CD8 (show CD8A Antibodies)(+) T-cell migratory behavior and effector functions.

  2. AEbeta7 is of key relevance for gut trafficking of inflammatory bowel disease (IBD) CD8(+) T cells and CD4(+) Th9 cells in vivo and mainly retention might account for this effect. These findings indicate that blockade of alphaEbeta7 in addition to alpha4beta7 may be particularly effective in intestinal disorders with expansion of CD8(+) and Th9 cells such as IBD.

  3. The CD103+CD4+/CD4 (show CD4 Antibodies)+ ratio does not accurately discriminate between sarcoidosis and other causes of lymphocytic alveolitis, neither alone nor in combination with the CD4 (show CD4 Antibodies)+/CD8 (show CD8A Antibodies)+ ratio, and is not a powerful marker for the diagnosis of sarcoidosis.

  4. CD103 expression in human dendritic cells is regulated differentially by retinoic acid and Toll (show TLR4 Antibodies)-like receptor ligands.

  5. detected CD103 tumor cells in 41% (16/39) of lymph node-involved adult T-cell leukemia/lymphoma

  6. Levels of GZMA (show GZMA Antibodies) and ITGAE mRNAs in colon tissues can identify patients with UC who are most likely to benefit from etrolizumab; expression levels decrease with etrolizumab administration in biomarker(high) patients.

  7. PD-1 (show PDCD1 Antibodies)(+)CD103(+) CD8 (show CD8A Antibodies) TIL (show TLR1 Antibodies) might regain functional antitumor activity, an effect that potentially could be augmented by immune modulation.

  8. This report highlights the diagnostic difficulties and the need of consensus in categorizing clonal CD103(+) lymphocytosis in patients with refractory celiac disease.

  9. Cell-sorting experiments demonstrated that IDO1 (show IDO1 Antibodies) expression is found in a subset of CD1a (show CD1A Antibodies)(+)CD14 (show NDUFA2 Antibodies)(-)langerin (show CD207 Antibodies)(+) cells, expressing CD103

  10. Report CD103 expression occurs most frequently in gastrointestinal T-cell lymphomas.

ITGAE Antigen Profile

Protein Summary

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Gene names and symbols associated with ITGAE

  • integrin alpha E, epithelial-associated (Itgae) antibody
  • integrin subunit alpha E (Itgae) antibody
  • integrin subunit alpha E (ITGAE) antibody
  • A530055J10 antibody
  • alpha-E1 antibody
  • alpha-M290 antibody
  • aM290 antibody
  • CD103 antibody
  • HUMINAE antibody

Protein level used designations for ITGAE

integrin alpha M290 , integrin alpha-E , integrin alpha E1, epithelial-associated , integrin, alpha E, epithelial-associated , HML-1 antigen , antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide , integrin alpha-IEL , mucosal lymphocyte 1 antigen

GENE ID SPECIES
16407 Mus musculus
83577 Rattus norvegicus
3682 Homo sapiens
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