anti-Interferon Activated Gene 202B (Ifi202b) Antibodies

Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Ifi202b 26388 Q9R002
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Showing 2 out of 2 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Rabbit Un-conjugated WB 100 μg 11 to 14 Days
Mouse Rabbit Un-conjugated WB 100 μg 2 to 3 Days

Top referenced anti-Ifi202b Antibodies

  1. Mouse (Murine) Polyclonal Ifi202b Primary Antibody for WB - ABIN4222423 : Panchanathan, Liu, Liu, Fang, Erickson, Pitha, Choubey: Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Ifi202b Interaction Partners

Mouse (Murine) Interferon Activated Gene 202B (Ifi202b) interaction partners

  1. Enforced expression of IFI16-b inhibits the activation of AIM2 inflammasome, whereas knockdown of IFI16-b augments interleukin-1b secretion triggered by dsDNA but not dsRNA Thus, cytoplasm-localized IFI16-b is functionally equivalent to mouse p202 that exerts an inhibitory effect on AIM2 inflammasome. .

  2. p202 promotes osteogenesis in mouse bone marrow stromal cells.

  3. Ifi202b and IFI16 have roles as obesity genes

  4. the expression level of Ifi202b showed the most sex difference in correlation with known immune-related genes

  5. These results, together with the reported data on p202 HINb, lead to an interaction model for full-length p202 and dsDNA which provides a conceivable mechanism for the negative regulation of Aim2 inflammasome activation by p202.

  6. p202 plays a role in mouse adipose-derived stem cell adipogenesis.

  7. Authors hypothesize that while p202 was evolutionarily selected to limit AIM2-mediated inflammation in some mouse strains, the same mechanism contributes to increased interferon production and lupus susceptibility.

  8. Ifi202b modulates fat accumulation through expression of adipogenic genes such as 11beta-Hsd1.

  9. Studies identify p202 as a regulator of murine BAFF.

  10. Our observations demonstrate that cell type and gender-dependent factors differentially regulate the expression of the Aim2 and p202 proteins

  11. Our findings indicate a potential role for Ifi202b in the suppressive capacity of peptide-induced regulatory CD8(+) Ti cells.

  12. expression of Aim2 protein is required to maintain the expression of the Fcgr2b gene and also predict epistatic interactions between the Ifi200 genes and the Fcgr2b gene within the Nba2 interval

  13. Findings delineate a new role of the IFN-gamma signaling pathway in regulating T cell proliferation and apoptosis through upregulating survivin and ifi202 expression.

  14. Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.

  15. Results suggest that Ifi202 expression in the kidney and immune organs significantly increased with disease progression in autoimmune glomerulonephritis.

  16. p202a can impair NF-kappaB activity both by inhibiting the binding to DNA of the transcriptionally active p65 homodimers and p50/p65 heterodimers and by boosting the binding of the repressive p50 homodimers

  17. Expression stimulation by Rb was dependent, in part, on a JunD/AP-1 DNA-binding site present in the 5'-regulatory region of the Ifi202 gene. transcriptional activation of Ifi202 gene by Rb/JunD may be important for cell growth and survival.

  18. increased levels of IL-6 in lupus contribute to up-regulation of p202

  19. Increased Ifi202 expression in B6.Nba2 mice increases their susceptibility to develop lupus, in part, by inhibiting p53-mediated apoptosis.

  20. Ifi202 is an important NF-kappaB activator in dendritic cells and is involved in IL-12 production, which may account for a T(h)1-prone phenotype of BWF1 mice

Ifi202b Antigen Profile

Protein Summary

Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53.

Gene names and symbols associated with Ifi202b

  • interferon activated gene 202B (Ifi202b) antibody
  • Ifbip-1 antibody
  • Ifi202 antibody
  • Ifi202a antibody
  • p202 antibody

Protein level used designations for Ifi202b

Interferon-activatable protein 202a (Ifi-202a) (Interferon-inducible protein p202a) , ifi-202 , interferon activated gene 202A , interferon-activable protein 202 , interferon-inducible protein p202 , lupus susceptibility protein p202

26388 Mus musculus
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