Interleukin 1 Receptor-Like 1 Proteins (IL1RL1)

The protein encoded by IL1RL1 is a member of the interleukin 1 receptor family. Additionally we are shipping IL1RL1 Antibodies (127) and IL1RL1 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL1RL1 17082 P14719
IL1RL1 9173 Q01638
Rat IL1RL1 IL1RL1 25556 Q62611
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Top IL1RL1 Proteins at

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Human Cells Human Fc Tag 100 μg Log in to see 20 to 21 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
Human Cells Human Un-conjugated 100 μg Log in to see 20 to 21 Days
HEK-293 Cells Human Fc Tag Human IL-1RL1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. Immobilized Human IL-33, Tag Free  with a linear range of 1.95-7.8 ng/mL. 200 μg Log in to see 21 to 31 Days
HEK-293 Cells Human Un-conjugated   25 μg Log in to see 10 to 12 Days
HEK-293 Cells Human DYKDDDDK-His Tag Validation with Western Blot 20 μg Log in to see 20 Days

IL1RL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, ,
Human , , , , ,
, , , ,

More Proteins for Interleukin 1 Receptor-Like 1 (IL1RL1) Interaction Partners

Mouse (Murine) Interleukin 1 Receptor-Like 1 (IL1RL1) interaction partners

  1. an increased prevalence in neonatal mortality was observed in litters from dams lacking ST2

  2. Taken together, the data demonstrate a critical role of MyD88 (show MYD88 Proteins) in DCs and of IL-33 (show IL33 Proteins) signaling via ST2 (show SULT2A1 Proteins) in MC903-induced Atopic dermatitis (AD). These data suggest that IL-33 (show IL33 Proteins)/IL-33R may be a therapeutic target of AD.

  3. Heligmosomoides polygyrus Alarmin Release Inhibitor (HpARI) prevents binding of active interleukin-33 (IL-33 (show IL33 Proteins)) to the IL-33 (show IL33 Proteins) receptor.

  4. this study shows that ST2 (show SULT2A1 Proteins) regulates early IL-13 (show IL13 Proteins) production in fungus-induced allergic airway inflammation

  5. mice deficient in the receptor for IL-33 (show IL33 Proteins) (Il1rl1-/-) demonstrated enhanced lung clearance of Aspergillus fumigatus

  6. This stuidy shown that the mRNA expression of IL-33 and ST2 receptors is increased in the CNS of Rocio virus-infected WT mice and that ST2(-/-) mice showed increased susceptibility to infection.

  7. Liver Treg cells show a high expression of ST2 (show SULT2A1 Proteins), a cellular receptor for tissue alarmin IL-33 (show IL33 Proteins), which is strongly upregulated in the liver of infected mice. These results illustrate the importance of IL-33 (show IL33 Proteins) in the suppressive function of liver Treg cells during Cytomegaloviruses (CMVs) infection.

  8. these studies establish a basal defect in eosinophilopoiesis in IL-33 (show IL33 Proteins)- and ST2 (show SULT2A1 Proteins)-deficient mice and a mechanism whereby IL-33 (show IL33 Proteins) supports eosinophils by driving both systemic IL-5 (show IL5 Proteins) production and the expansion of IL-5Ralpha-expressing precursor cells

  9. These results shed light on endogenous IL-33/ST2 signaling as a potential immune regulatory mechanism that serves to promote beneficial microglial responses and mitigate ischemic brain injury after stroke.

  10. Plasmodium berghei infection triggered a dramatic increase of IL-33 expression by oligodendrocytes, through ST2 pathway.

Human Interleukin 1 Receptor-Like 1 (IL1RL1) interaction partners

  1. Foxp3 (show FOXP3 Proteins)(+) cells in the brains of Multiple sclerosis patients predominantly produce interleukin-10 (IL-10 (show IL10 Proteins)) and show high expression of the IL-33 (show IL33 Proteins) receptor ST2 (show SULT2A1 Proteins).

  2. In patients with stable mild to moderate chronic heart failure with reduced ventricular ejection fraction, a single measurement of sST2 (show SSTR2 Proteins) protein and glucose were independent variables for hospitalization due to worsening CHF over a 1-year follow-up period.

  3. present study highlights significant associations between ST2 and inflammatory bowel disease.

  4. Data show that interleukin-2 receptor alpha (show IL2RA Proteins), tumor necrosis factor receptor 1 (show TNFRSF1A Proteins), serum STimulation-2 (IL1RL1 gene product), and regenerating islet-derived 3-alpha (show REG3A Proteins) were significantly associated with non-relapse mortality.

  5. Serum IL-33 (show IL33 Proteins) and sST2 (show SSTR2 Proteins) levels, and CD4 (show CD4 Proteins)+ST2L+ expression in peripheral blood mononuclear cells are closely associated with HIV-1 infection and immune reconstitution in patients received highly-active antiretroviral therapy.

  6. Elevated levels of sST2 (show SSTR2 Proteins) concentration in stable coronary heart disease patients may independently predict short- and long-term risk for fatal CVD events and total mortality but not non-fatal CVD events.

  7. Patients with severe aortic valve stenosis present elevated sST2 (show SSTR2 Proteins) levels. Left ventricular global longitudinal strain resulted the only independent predictor of sST2 (show SSTR2 Proteins) levels.

  8. The Il1RL1 rs950880 AA homozygote is an independent predictor of all-cause mortality in coronary artery disease and peripheral arterial disease patients.

  9. In a cohort of hypertensive heart failure subjects, soluble ST2 correlates significantly with indicators of right ventricular function.

  10. Data provide evidence that increased IL-33/ST2 levels in patients with chronic kidney disease are an indicator of increased inflammation, impaired endothelial functions, and cardiovascular events.

IL1RL1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with IL1RL1

  • interleukin 1 receptor-like 1 (Il1rl1)
  • interleukin 1 receptor like 1 (IL1RL1)
  • DER4 protein
  • FIT-1 protein
  • FIT1 protein
  • IL33R protein
  • Ly84 protein
  • ST2 protein
  • St2-rs1 protein
  • ST2L protein
  • ST2V protein
  • T1 protein
  • T1/ST2 protein

Protein level used designations for IL1RL1

T1 , interleukin-1 receptor-like 1 , lymphocyte antigen 84 , protein T1 , growth stimulation-expressed , homolog of mouse growth stimulation-expressed , interleukin 1 receptor-related protein , fos-responsive gene 1 protein

17082 Mus musculus
9173 Homo sapiens
611442 Canis lupus familiaris
374136 Gallus gallus
25556 Rattus norvegicus
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