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IL1RL1 Protein (His tag)

This Recombinant IL1RL1 protein is expressed in Human Cells.
Catalog No. ABIN7320553
$345.12
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Quick Overview for IL1RL1 Protein (His tag) (ABIN7320553)

Target

See all IL1RL1 Proteins
IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Protein Type

Recombinant

Origin

  • 17
  • 5
Mouse

Source

  • 9
  • 4
  • 3
  • 2
  • 2
  • 2
Human Cells

Purity

> 95 % as determined by SDS-PAGE
  • Purification tag / Conjugate

    This IL1RL1 protein is labelled with His tag.

    Purpose

    Recombinant Mouse IL1RL1/ST2 Protein (His Tag)

    Sequence

    Ser27-Ala337

    Characteristics

    Recombinant Mouse Interleukin-1 receptor-like 1 is produced by our Mammalian expression system and the target gene encoding Ser27-Ala337 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

    Alternative Name

    IL1RL1/ST2

    Background

    Background: ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.

    Synonym: Interleukin-1 receptor-like 1, Lymphocyte antigen 84, Protein ST2, Protein T1, Il1rl1, DER4, Fit-1, IL-1 R4, IL-1RL1, IL-33R, Ly84, ST2L, ST2V, suppression of tumorigenicity 2

    Molecular Weight

    36.6 kDa
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