IL1RL1 Protein (AA 19-328) (His tag)
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- Target See all IL1RL1 Proteins
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-328
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL1RL1 protein is labelled with His tag.
- Purpose
- Human IL-1RL1/ST2 Protein
- Sequence
- Lys19-Phe328
- Characteristics
- Recombinant Human IL-1RL1/ST2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys19-Phe328.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-33, No Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IL-1RL1, His Tag with the EC50 of 3ng/ml determined by ELISA. See testing image for detail.
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Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) (Active) protein (His tag)
IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 1 Receptor-Like 1 (IL1RL1) protein (His tag)IL1RL1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 1-328), (Isoform 2) (Active) protein (Fc Tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 350-556) protein (His tag)Crystallography grade IL1RL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 356-567) protein (His tag)Crystallography grade IL1RL1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) protein (His tag)Crystallography grade IL1RL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 27-332) protein (His tag)Crystallography grade IL1RL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-556) protein (rho-1D4 tag)Crystallography grade IL1RL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 27-567) protein (rho-1D4 tag)Crystallography grade IL1RL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-323) (Active) protein (Fc Tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- Alternative Name
- IL-1RL1 (IL1RL1 Products)
- Synonyms
- DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
- Background
- IL1RL1(also known as ST2) is a member of the IL1 receptor family and serves as the receptor for IL-33. The ST2 protein has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect. ST2/IL-33 signaling may play an important role in intestinal disease.
- Molecular Weight
- 36 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
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