Interleukin 25 (IL25) ELISA Kits

Human Interleukin 25 (IL25) interaction partners

1. Nasal IL-25 predicts the response to oral corticosteroids.

2. IL-25 (also known as IL-17E) is a member of the IL-17 cytokine family and plays a variety of roles in different inflammatory murine models, such as asthma, atopic dermatitis, and pulmonary fibrosis.

3. expression of IL-17A, E, and F and their receptors in non-small-cell lung cancer; data suggest that IL-17A, E, F and their receptors IL-17RA, RB, RC may be involved in the pathogenesis of non-small cell lung cancer

4. MiR-31a-5p suppression decreased IL-25 expression, inhibited IL-1beta, IL-6, IL-8, and TNF-alpha secretions, and decreased proliferation in CC-2511 cells under hyperthermic stress.

5. study provides a comprehensive characterization of the thymic stroma and identifies a new tuft-like thymic epithelial cell population, which is critical for shaping the immune niche in the thymus

6. The data demonstrate that an IL-17-induced autoregulatory circuit in keratinocytes is mediated by IL-25 and suggest that this circuit could be targeted in the treatment of psoriasis patients.

7. this review details the structural characteristics, expression patterns, responder cells, biological properties, and role of IL-25 in disease pathogenesis

8. this study shows that IL-25 reduces Th17 cells and inflammatory responses in human peripheral blood mononuclear cells

9. Endometrial stromal cells differentiate into decidual stromal cells in the presence of ovarian hormones, resulting in the upregulation of IL25/IL17RB expression in endometrial stromal cells.

10. In conclusion, the findings of the present study suggest that IL-25 but not IL-33 might contribute to the pathogenesis of chronic eosinophilic inflammation of the lung in patients with CEP.

11. Nasal Il-25 is overexpressed in patients with chronic rhinosinusitis with nasal polyps and airway hypersensitiveness.

12. IL-4 signaling up-regulates the IL-25 axis in human monocytic cells, and IL-25 may provide autocrine signals in monocytes and macrophages to sustain IL-17Rb expression and predispose to alternative activation.

13. IL-25-induced activation of nasal fibroblast and its association with the remodeling of chronic rhinosinusitis with nasal polyposis

14. The authors concluded that IL-25 provides protection from amebiasis, which is dependent upon intestinal eosinophils and suppression of TNF-alpha.

15. Inhibition of IL-25 resulted in decreased type 2 T cells and macrophages in the primary tumor microenvironments, both reported to enhance breast tumor invasion and subsequent metastasis to the lung.

16. Our findings suggest that the IL-25/IL-25R axis may play an important role in promoting the recruitment and proinflammatory function of eosinophils in allergic asthma.

17. Chronic rhinosinusitis with nasal polyps (CRSwNP) epithelial cells release TSLP and IL-25 when stimulated by poly(I:C) but not by DP or AF, suggesting that viral infection may contribute to maintain and amplify the T2 immune response seen in CRSwNP.

18. Increased induction and expression of TSLP, IL-25, and IL-33 from nasal epithelial cells contribute to the pathophysiology of eosinophilic chronic rhinosinusitis.

19. Women with endometriosis showed significantly higher levels of IL-25 in their PF (p=0.019) compared to controls. IL-25 levels did not correlate with the stage of endometriosis.

20. IL-8 and IL-25 are targets of miR-20b.

Mouse (Murine) Interleukin 25 (IL25) interaction partners

1. Prevention of food allergy development and suppression of established food allergy by neutralization of thymic stromal lymphopoietin, IL-25, and IL-33.

2. endogenous IL-25 has an atheroprotective role in the murine aortic arch has potential implications for atherosclerosis development and management in humans

3. study provides a comprehensive characterization of the thymic stroma and identifies a new tuft-like thymic epithelial cell population, which is critical for shaping the immune niche in the thymus

4. these data suggest that IL-25 plays an inhibitory role in the growth and development of colonic tumors.

5. this study shows that the signaling axis of microRNA-31/interleukin-25 regulates Th1/Th17-mediated inflammation response in colitis

6. IL-25 is a component of the immune response that is regulated by a healthy microbiota and reduces pathology associated with Clostridium difficile Infection.

7. study concludes that IL-33 and TSLP are required for epithelial cell IL-25 expression, mucous metaplasia, and ILC2 expansion following early-life rhinovirus infection

8. IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease

9. data suggested that deletion of Shp2 impaired IL-25 production in bronchial epithelial cells in vitro, but might yet have minor influence on OVA-induced allergic reaction in vivo

10. study showed that IL-25 promoted the accumulation of ICOS and T1/ST2 on nuocytes, further induced the pro-inflammatory Th2 cells, and promoted Th2 cytokine responses in OVA-induced airway inflammation

11. Inhibition of IL-25 resulted in decreased type 2 T cells and macrophages in the primary tumor microenvironments, both reported to enhance breast tumor invasion and subsequent metastasis to the lung.

12. this study shows that activation of primed TH2 cells occurs independently of group 2 innate lymphoid cells or their cytokines but that the effector function of both cell types was dependent on combinatorial exposure to IL-33, IL-25 and TSLP

13. These data demonstrate that IL-25 is critical for host protective immunity against H. polygyrus bakeri infection, highlighting its potential application as a therapeutic agent against parasitic nematode infection worldwide.

14. Findings indicate that the release of interleukin 25 (IL-25) from tumour-associated fibroblasts (TAFs) may serve as a check point for control of mammary tumour metastasis.

15. IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy.

16. IL-22 restrains tapeworm-mediated protection against colitis via regulation of IL-25 expression

17. IL-25 promotes the function of CD4+CD25+ T regulatory cells and prolongs skin-graft survival in murine models

18. IL-25 and IL-33 are critical for induction of Th2-type cytokine-mediated allergic airway eosinophilia, but not Th17-type cytokine-mediated airway neutrophilia, at the local sites of lungs in the challenge phase of mice sensitized EC with OVA

19. Suggest that chronic exposure of murine airways to IL-25 alone is able to reproduce a local angiogenic milieu in asthmatic mice.

20. we have demonstrated that the expression of ET-1 and IL-25 was coordinately upregulated in the lesional keratinocytes of patients with AD and a murine AD model.