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IL-25 ELISA Kit

IL25 Reactivity: Mouse Colorimetric Sandwich ELISA 0.03-2.0 ng/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum
Catalog No. ABIN4986951
  • Target See all IL-25 (IL25) ELISA Kits
    IL-25 (IL25) (Interleukin 25 (IL25))
    Reactivity
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Detection Range
    0.03-2.0 ng/mL
    Minimum Detection Limit
    0.03 ng/mL
    Application
    ELISA
    Sample Type
    Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
    Analytical Method
    Quantitative
    Specificity
    Natural and recombinant Mouse IL-25(IL-17E) Ligand
    Sensitivity
    15 pg/mL
    Material not included
    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
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  • Application Notes
    Detection Wavelength: 450 nm
    Sample Volume
    20 μL
    Assay Time
    3 h
    Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C
  • Target See all IL-25 (IL25) ELISA Kits
    IL-25 (IL25) (Interleukin 25 (IL25))
    Alternative Name
    IL-25(IL-17E) (IL25 Products)
    Synonyms
    IL17E ELISA Kit, IL-17e ELISA Kit, Il17e ELISA Kit, IL25 ELISA Kit, RGD1561632 ELISA Kit, interleukin 25 ELISA Kit, IL25 ELISA Kit, Il25 ELISA Kit
    Background
    IL-25 (also known as IL-17E) is a member of the IL-17 family of proinflammatory cytokines, which includes IL-17A, IL-17B, IL-17C, IL-17F and IL-17A/F. IL-17E is found at low levels in various peripheral tissues. It is a proinflammatory cytokine that promotes airway eosinophilia in mice. IL-17E plays a role in Th2 type inflammatory diseases, such as asthma and atopic dermatitis. IL-25 induces elevatedgene expression of IL-4, IL-5 and IL-13 in multiple tissues and results in T helper 2 (TH2)-type immune responses (increased serumIgE levels) and pathologic changes in the lungsand digestive tract with eosinophilic infiltrates, increased mucusproduction, epithelial cell hyperplasia and overall amplified allergicinflammation. IL-25 shares the receptor IL-17RB with IL-17B, although it binds with much higher affinity than IL-17B.
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