Interleukin 28B (Interferon, lambda 3) Proteins (IL28B)

IL28B encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping Interleukin 28B (Interferon, lambda 3) Antibodies (112) and Interleukin 28B (Interferon, lambda 3) Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat IL28B IL28B 685840  
IL28B 338374 Q8CGK6
IL28B 282617 Q8IZI9
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Top Interleukin 28B (Interferon, lambda 3) Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Human Cells Human His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HEK-293 Cells Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$1,180.00
Details
Mammalian Cells Human Un-conjugated   10 μg Log in to see 4 Days
$161.70
Details
Human Cells Mouse His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
Yeast Human His tag SDS-PAGE 100 μg Log in to see 20 to 21 Days
$547.80
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Human Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
Details
Insect Cells Human His tag   50 μg Log in to see 2 to 3 Days
$444.37
Details
CHO Cells Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$275.00
Details

IL28B Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , , , , , ,

More Proteins for Interleukin 28B (Interferon, lambda 3) (IL28B) Interaction Partners

Mouse (Murine) Interleukin 28B (Interferon, lambda 3) (IL28B) interaction partners

  1. results suggest that IL-28B induces more mature NK cells to defend against viruses, in addition to its direct antiviral activity

  2. IL-28B down-regulates Tregs following subunit vaccine ESAT6-Ag85B-Mpt64(190-198)-Mtb8.4-HspX (show HSP Proteins) vaccination but does not improve the protective immune responses.

  3. the role of IFN-lambda in IDO (show IDO1 Proteins) regulation was investigated after influenza infection of respiratory epithelial cells.

  4. Data indicate that rotavirus infection induces production of interferon (show IFNA Proteins)-lambda (IFN-lambda) and interleukin 22 (IL-22 (show IL22 Proteins)) by intestinal epithelial cells.

  5. Acritical role of IL-28 cytokines is in controlling T cell responses in vivo through the modulation of lung CD11c (show ITGAX Proteins)(+) DC function in experimental allergic asthma.

  6. IFN-alpha (show IFNA Proteins), IFN-beta (show IFNB1 Proteins), and IFN-gamma (show IFNG Proteins) were observed in the anterior segment of injected eyes through 72 hours and mRNA levels of IFN-beta (show IFNB1 Proteins) and IFN-gamma (show IFNG Proteins) were increased in virus-infected eyes 48 to 120 hours after herpes simplex infection

  7. the duration of IFNlambda signaling to JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) is different from that of IFNalpha

  8. intranasal influenza A virus infection leads to the robust type III IFN induction in the lungs of both WT and IFNAR (show IFNAR1 Proteins)-/- mice

  9. IL-28A (show IL28A Proteins) emerges as a key regulatory cytokine with pathogenic function in T-cell-mediated liver injury

  10. Type III interferon (show IFNA Proteins)/IL-28 targets a specific subset of cells and contributes to the antiviral response evoked by Toll (show TLR4 Proteins)-like receptors, largely mediated by inducing an antiviral state in epithelial cells.

Human Interleukin 28B (Interferon, lambda 3) (IL28B) interaction partners

  1. Results demonstrated genetic variations of IL-28B might impact liver function recovery after transplantation by influencing peripheral platelet counts and reducing liver inflammation, but weak association with transplant etiologies.

  2. The results obtained suggest that both studied IL28B gene SNPs (single nucleotide polymorphisms), as well as the IL10 (show IL10 Proteins) gene rs1800872 SNP are associated with predisposition to tick-borne encephalitis in Russian population.

  3. IL-28B genotyping may be useful for directing patients towards lower cost therapies, and rationing use of costly direct antivirals for use in those individuals showing genetic risk.

  4. the IFNL3 rs 12979860 CC genotype may be negatively associated with hepatic steatosis in Asian chronic hepatitis C patients.

  5. IL-28B rs12979860 genotype was significantly related to severe necroinflammatory activity (NIA) grade of chronic hepatitis C patients.

  6. Data show that the genotype distributions of IFNL3 and IFNL4 variants (rs4803217, rs368234815, rs117648444, and rs12979860) were in Hardy-Weinberg equilibrium.

  7. In Taiwan, chronic hepatitis C (CHC) patients have a lower frequency of favorable IL28B TT genotype than healthy controls. Among patients with CHC, the frequency of TT genotype is higher in HCV genotype 2 patients than in HCV genotype 1 patients. In addition, CHC patients with TT genotype, particularly females, have a lower likelihood of advanced fibrosis.

  8. IFNL3 SNPs genotyped have shown no association with ribavirin treatment in hepatitis C patients with genotype 3.

  9. monocytes from carriers of an IL-28B T/T genotype display a reduced ability to stimulate NK cell activity

  10. alterations in IL28B SNP genotype may occur after living donor liver transplantation, leading to modifications in the host genome or donor proteome by HCV.

Interleukin 28B (Interferon, lambda 3) (IL28B) Protein Profile

Protein Summary

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Gene names and symbols associated with IL28B

  • interferon, lambda 3 (Ifnl3)
  • interferon lambda 3 (IFNL3)
  • interferon lambda 3 (Ifnl3)
  • IFL-1 protein
  • IL-28B protein
  • Il28 protein
  • IL28B protein
  • IL28C protein
  • INF-alpha protein
  • INF-lambda protein

Protein level used designations for IL28B

interleukin 28B , interleukin-29 , IFN-lambda-3 , interferon alpha , interferon lambda-3 , interleukin 28 , interleukin-28B , IFN-lambda-4 , IL-28C , cytokine Zcyto22 , interferon lambda-4 , interferon, lambda 4 , interleukin 28B (interferon, lambda 3) , interleukin 28C , interleukin-28C

GENE ID SPECIES
685840 Rattus norvegicus
100620067 Bos taurus
338374 Mus musculus
282617 Homo sapiens
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