IL28B Protein
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- Target See all IL28B Proteins
- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Recombinant Human Interleukin-28B is produced by our Mammalian expression system and the target gene encoding Val22-Val196 is expressed.
- Characteristics
- Extracellular Domain Protein
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL28B Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
- Alternative Name
- IL-28B (IL28B Products)
- Synonyms
- Il28b Protein, IFL-1 Protein, IL-28B Protein, INF-alpha Protein, INF-lambda Protein, Il28 Protein, IL28B Protein, IL28C Protein, interferon, lambda 3 Protein, interferon lambda 3 Protein, Ifnl3 Protein, IFNL3 Protein
- Background
- Interleukin-28B, IL-28B, Cytokine Zcyto22, Interferon Lambda-3, IFN-Lambda-3, Interferon Lambda-4, IFN-Lambda-4, Interleukin-28C, IL-28C, IL28B, IFNL3, IFNL4, IL28C, ZCYTO22Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
- Molecular Weight
- 19.6 KDa
- UniProt
- Q8IZI9
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