anti-Inversin (INVS) Antibodies

INVS encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. Additionally we are shipping Inversin Kits (6) and Inversin Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
INVS 27130 Q9Y283
INVS 16348 O89019
INVS 313228  
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Top anti-Inversin Antibodies at

Showing 5 out of 7 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using INVS antibody. 100 μL Log in to see 16 Days
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.12 KDa) . 50 μL Log in to see 11 to 12 Days
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   50 μL Log in to see 13 to 16 Days
Human Rabbit Un-conjugated ELISA, IF/ICC, IHC, WB   50 μL Log in to see 11 to 16 Days
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   50 μL Log in to see 2 to 3 Days

INVS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality

Mouse (Murine)

Rat (Rattus)

Top referenced anti-Inversin Antibodies

  1. Human Polyclonal Inversin Primary Antibody for ELISA, WB - ABIN565339 : Cox, Sallustio, Serino, Pontrelli, Verrienti, Pesce, Torres, Ancona, Stifanelli, Zaza, Schena: Altered modulation of WNT-beta-catenin and PI3K/Akt pathways in IgA nephropathy. in Kidney international 2010 (PubMed)

More Antibodies against Inversin Interaction Partners

Xenopus laevis Inversin (INVS) interaction partners

  1. Inversin relays Frizzled-8 (show FZD8 Antibodies) signals to promote proximal pronephros development.

  2. The present study indicates that calmodulin binding sites (IQ motifs) are crucial in controlling the biological activity of both mouse and Xenopus inv proteins

Human Inversin (INVS) interaction partners

  1. Collectively, these results indicated that inversin might promote the tumorigenicity of lung cancer cells and serve as a novel therapeutic target of non-small cell lung cancer.

  2. Akt (show AKT1 Antibodies) phosphorylates inversin at amino acids 864-866 that are required not only for Akt (show AKT1 Antibodies) interaction, but also for inversin dimerization.

  3. Truncating mutations in NPHP2 gene is associated with nephronophthisis-related ciliopathy.

  4. ANKS6 (show ANKS6 Antibodies) as a new NPHP family member that assembles a distinct module of nephronophthisis-associated proteins, encompassing NEK8 (show NEK9 Antibodies), INVS and NPHP3 (show NPHP3 Antibodies).

  5. INVS mutation can cause juvenile nephronophthisis with abnormal reactivity of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  6. has conserved ankyrin repeat and IQ domains and interacts with calmodulin

  7. analysis of a homozygous mutation in exon 13 of inversin (INVS) (C2719T, R907X) in a patient with retinitis pigmentosa and renal failure [case report]

  8. Thus, although considered a common variant, inv(10)(p11.2q21.2) has a single ancestral founder among northern Europeans.

  9. Cystic kidney disease has been linked to mutations in the Invs gene in mice with an inversion of embryonic turning (inv/inv) and the INVS (NPHP2) gene in human infantile nephronophthisis (NPH (show TENC1 Antibodies)).

  10. screened 43 families with infantile nephronophthisis (ESRD less than 5 years of age) for NPHP2 and NPHP3 (show NPHP3 Antibodies) mutations and determined genotype-phenotype correlations

Mouse (Murine) Inversin (INVS) interaction partners

  1. We constructed sub-congenic lines to more specifically localize the modifier and have determined it resides in a 3.2 Mb interval containing 28 genes. These include Invs and Anks6 (show ANKS6 Antibodies), which are both excellent candidates for the modifier as mutations in these genes result in PKD (show PRKD1 Antibodies) and both genes are known to genetically and physically interact with Nek8 (show NEK8 Antibodies).

  2. Ciliary abnormalities are associated with nphp2 mutant mice.

  3. Loss of NPHP2 causes ciliogenesis defects.

  4. the significance of Inversin in controlling cell migration processes

  5. Nek8 (show NEK8 Antibodies) acts downstream of Inv function

  6. Inv acts as a molecular anchor for Nphp3 (show NPHP3 Antibodies) and Nek8 (show NEK8 Antibodies) in the proximal segment of primary cilia.

  7. the inv gene product functions in several cellular compartments, including the nucleus and cell-cell adhesion sites

  8. Molecular cloning of a gene for inversion of embryo turning (inv) with cystic kidney. Deduced amino acid sequence shows 15 successive repeats of Ank (show ANKH Antibodies)/Swi6 motif in its N-terminal domain. Mutation causes situs inversus and cysts in kidney in inv mutant.

  9. inv has a role in kidney disease: inv mutant mouse has renal cysts resembling infantile NPHP2

  10. The localization of inversin in distal tubules in the kidney and in extrarenal tissues suggests that the expression of this protein has an important function in a variety of organs.

Zebrafish Inversin (INVS) interaction partners

  1. Nek8 (show NEK8 Antibodies) acts downstream of Inv function

Inversin (INVS) Antigen Profile

Protein Summary

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with anti-Inversin (INVS) Antibodies

  • inversin S homeolog (invs.S) antibody
  • inversin (INVS) antibody
  • inversin (Bm1_38710) antibody
  • inversin (PTRG_09181) antibody
  • Inversin (EAMY_RS33690) antibody
  • inversin (LOAG_11716) antibody
  • inversin (invs) antibody
  • inversin (Invs) antibody
  • INV antibody
  • INVS antibody
  • invs-a antibody
  • MGC140477 antibody
  • NPH2 antibody
  • Nphp2 antibody
  • RGD1563359 antibody
  • wu:fe47e11 antibody

Protein level used designations for anti-Inversin (INVS) Antibodies

inversin , inversion of embryo turning homolog , inversion of embryonic turning , nephrocystin-2 , inversion of embryo turning protein , nephrocystin 2

378491 Xenopus laevis
473146 Pan troglodytes
529698 Bos taurus
6102626 Brugia malayi
6347469 Pyrenophora tritici-repentis Pt-1C-BFP
8912192 Erwinia amylovora CFBP1430
9949175 Loa loa
100010929 Monodelphis domestica
100075447 Ornithorhynchus anatinus
100144697 Xenopus (Silurana) tropicalis
100344027 Oryctolagus cuniculus
100453593 Pongo abelii
100594079 Nomascus leucogenys
27130 Homo sapiens
16348 Mus musculus
313228 Rattus norvegicus
395234 Gallus gallus
442950 Canis lupus familiaris
245946 Danio rerio
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