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IRX5 encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Additionally we are shipping IRX5 Proteins (5) and many more products for this protein.
Showing 10 out of 48 products:
A total of three nonsynonymous mutations (p.Gln240Glu, p.Ser298Asn and p.Ala381Glu) of the IRX1 (show IRX3 Antibodies) gene were verified in 215 nonsyndromic congenital heart disease patients.
this is the first genome-wide association study of Rheumatoid Factor positivity in Rheumatoid Arthritis. Variation at the IRX1 (show IRX3 Antibodies) locus on chromosome 5p15.3 is associated with the presence of Rheumatoid Factor. Our findings indicate that IRX1 (show IRX3 Antibodies) and HLA-DRB1 (show HLA-DRB1 Antibodies) are the strongest genetic factors for Rheumatoid Factor production in Rheumatoid Arthritis.
Authors identify a novel association that implicates the IRX5 gene region in obesity and compare our results with previously derived interaction data for the region.
In osteosarcoma cells and lines, IRX1 (show IRX3 Antibodies) overexpression was associated with hypomethylation of its own promoter. Experimental modulation in cell lines altered migration, invasion, and resistance to anoikis in vitro, and influenced lung metastasis in mice.
Findings suggest that methylation-associated down-regulation of EBF3 (show MAPRE3 Antibodies) and IRX1 (show IRX3 Antibodies) genes may play an important role in a pathogenic effect of TGF-beta (show TGFB1 Antibodies) on RASFs.
Helicobacter pylori infection contributes to IRX1 (show IRX3 Antibodies) promoter methylation in gastric mucosa.
enforcing IRX1 (show IRX3 Antibodies) expression effectively suppresses peritoneal spreading and pulmonary metastasis via anti-angiogenesis and anti-VM mechanisms, in addition to previously found cell growth and invasion.
Homeobox (show Lbx1 Antibodies) gene IRX1 (show IRX3 Antibodies) is a tumor suppressor gene in gastric carcinoma.
Results verify IRX1 (show IRX3 Antibodies), EBF3 (show MAPRE3 Antibodies), SLC5A8 (show SLC5A8 Antibodies), SEPT9 (show SEPT9 Antibodies), and FUSSEL18 (show SKOR2 Antibodies) as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1 (show IRX3 Antibodies), EBF3 (show MAPRE3 Antibodies), SLC5A8 (show SLC5A8 Antibodies), and SEPT9 (show SEPT9 Antibodies).
Irx5 is involved in the regulation of both the cell cycle and apoptosis in human prostate cancer cells
Irx3 and Irx5 (Irx3/5) are essential in the initiating limb bud to specify progenitors of the femur, tibia, and digit 1.
postnatal Irx3 (show IRX3 Antibodies) activity can be repressed by Irx5
Regulates the development of type 2 and type 3 cone bipolar cells independently of visual system homeobox 1 (Vsx-1 (show VSX1 Antibodies)).
Irx5 establishes the cardiac ventricular repolarization gradient.
Iroquois related homeobox 5 (Irx5 (show IRX2 Antibodies)) transcription factor controls specific aspects of visual function in circuits of the mammalian retina.
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13.
homeodomain protein IRX-2A
, homeodomain protein IRXB2
, iroquois-class homeodomain protein IRX-5
, homeodomain protein IRXA1
, iroquois homeobox protein 1
, iroquois-class homeodomain protein IRX-1
, iroquois homeobox 5
, iroquois homeobox protein 5
, iroquois-class homeodomain protein irx-5
, Iroquois homeobox protein 5
, iroquois-5 homeobox transcription factor
, LOW QUALITY PROTEIN: iroquois-class homeodomain protein IRX-5