IRX5 antibody (Middle Region)

Catalog No. ABIN2780012

The Rabbit Polyclonal anti-IRX5 antibody (ABIN2780012) specifically detects IRX5 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog and Pig samples.

Quick Overview for IRX5 antibody (Middle Region) (ABIN2780012)

Target: IRX5 (Iroquois Homeobox Protein 5 (IRX5))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRX5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRX5 Antibody

Binding Specificity: Middle Region

Purpose: Irx5 Antibody - middle region

Sequence: ENIDLEKNDE DEPQKPEDKG DLEGPESGGA EQKATAGCER LQGPLSPAGK

Predicted Reactivity: Cow: 93%, Dog: 92%, Guinea Pig: 86%, Horse: 100%, Human: 93%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Irx5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse Irx5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37245-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IRX5

Target: IRX5 (Iroquois Homeobox Protein 5 (IRX5))

Alternative Name: Irx5

Background:

Background Information: Irx5 establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene.Irx5 is required for retinal cone bipolar cell differentiation.Irx5 may regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina.

Gene Name: Iroquois related homeobox 5 (Drosophila)

Alternative Symbols: -

Protein Name: Iroquois-class homeodomain protein IRX-5

Molecular Weight: 51kDa

Gene ID: 54352

NCBI Accession: NP_061296

UniProt: Q9JKQ4