Isoleucyl-tRNA Synthetase Proteins (IARS)

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Additionally we are shipping IARS Antibodies (31) and IARS Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IARS 105148 Q8BU30
Rat IARS IARS 306804  
IARS 3376 P41252
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Top IARS Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg 15 to 18 Days
Baculovirus Human Un-conjugated   100 μg 9 to 11 Days

IARS Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,

More Proteins for Isoleucyl-tRNA Synthetase (IARS) Interaction Partners

Zebrafish Isoleucyl-tRNA Synthetase (IARS) interaction partners

  1. Mutations in isoleucyl tRNA synthetase (iars(y68)) leads to increased branching angiogenesis in developing zebrafish.

Cow (Bovine) Isoleucyl-tRNA Synthetase (IARS) interaction partners

  1. Its mutation causes prenatal death in Japanese Black cattle

Human Isoleucyl-tRNA Synthetase (IARS) interaction partners

  1. Our report presents new evidence that recessive mutations inIARSgene are associated with characteristic clinical phenotype suchas infantile hepatopathy, growth retardation, facial dysmorphism,hypotonia, intellectual disability with no speech .

  2. bi-allelic mutations in cytosolic isoleucyl-tRNA synthetase (IARS) have been described in three individuals with growth delay, hepatic dysfunction, and neurodevelopmental disabilities. Here we report an additional subject with this condition identified by whole-exome sequencing. Our findings support the association between this disorder and neonatal cholestasis with distinct liver pathology

  3. Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy

IARS Protein Profile

Protein Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.

Gene names and symbols associated with IARS

  • isoleucyl-tRNA synthetase (iars)
  • isoleucyl-tRNA synthetase (IARS)
  • tRNA synthetase class I (I, L, M and V) family protein (OVA2)
  • isoleucyl-tRNA synthetase (ileS)
  • isoleucine--tRNA ligase (MBAR_RS19160)
  • isoleucyl-tRNA synthetase (Rmag_0340)
  • isoleucyl-tRNA synthetase, cytoplasmic (ANI_1_964074)
  • isoleucyl-tRNA synthetase (CHLREDRAFT_106327)
  • isoleucyl-tRNA synthetase, cytoplasmic (EDI_049880)
  • isoleucine--tRNA ligase (OE_RS08520)
  • isoleucyl-tRNA synthetase, cytoplasmic (AOR_1_1912194)
  • isoleucine-tRNA synthetase (Iars)
  • isoleucyl-tRNA synthetase (Iars)
  • 2510016L12Rik protein
  • AI327140 protein
  • An08g06770 protein
  • AO090012000505 protein
  • AU044614 protein
  • E430001P04Rik protein
  • ECK0027 protein
  • fi46h05 protein
  • IARS1 protein
  • Iarsl protein
  • ILERS protein
  • ILRS protein
  • ilvS protein
  • IRS protein
  • JW0024 protein
  • K19E20.18 protein
  • K19E20_18 protein
  • ovule abortion 2 protein
  • PRO0785 protein
  • wu:fi46h05 protein
  • zgc:63790 protein

Protein level used designations for IARS

isoleucyl-tRNA synthetase, cytoplasmic , isoleucine tRNA synthetase , isoleucyl-tRNA synthetase , IRS , ileRS , isoleucine--tRNA ligase, cytoplasmic , isoleucine-tRNA synthetase , isoleucyl tRNA synthetase , isoleucine tRNA ligase 1, cytoplasmic

334393 Danio rerio
509885 Bos taurus
834962 Arabidopsis thaliana
944761 Escherichia coli str. K-12 substr. MG1655
1444584 Aeropyrum pernix K1
1791528 Rhodopirellula baltica SH 1
2774814 Thermus thermophilus HB27
3168241 Thermus thermophilus HB8
3233369 Ehrlichia ruminantium str. Welgevonden
3337999 Chlamydophila abortus S26/3
3626315 Methanosarcina barkeri str. Fusaro
4554628 Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica)
4982994 Aspergillus niger CBS 513.88
5724458 Chlamydomonas reinhardtii
5883630 Entamoeba dispar SAW760
5953285 Halobacterium salinarum R1
5987985 Aspergillus oryzae RIB40
7039565 Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2
7738390 Deinococcus deserti VCD115
8468684 Clostridium difficile R20291
8528201 Blattabacterium sp. (Periplaneta americana) str. BPLAN
8680359 Methanocella paludicola SANAE
100551015 Meleagris gallopavo
100554864 Anolis carolinensis
100597959 Nomascus leucogenys
105148 Mus musculus
306804 Rattus norvegicus
3376 Homo sapiens
415957 Gallus gallus
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