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Histone demethylase required for brain development. Additionally we are shipping and many more products for this protein.
Showing 10 out of 35 products:
KDM7A mediates TNF-alpha (show TNF Antibodies)-induced ICAM1 (show ICAM1 Antibodies) protein upregulation.
G9a (show EHMT2 Antibodies) promotes H3K27 methylation of the E-cadherin (show CDH1 Antibodies) promoter by upregulating PCL3 (show PHF19 Antibodies) to increase PRC2 promoter recruitment and by downregulating the H3K27 demethylase (show MBD2 Antibodies) KDM7A to silence E-cadherin (show CDH1 Antibodies) gene
Histone modifier genes (JMJD1C (show JMJD1C Antibodies), RREB1 (show RREB1 Antibodies), MINA (show MINA Antibodies), KDM7A) alter conotruncal heart phenotypes in 22q11.2 deletion syndrome.
increased JHDM1D expression suppresses tumor growth by down-regulating angiogenesis under nutrient starvation
KIAA1718 is a dual-specificity histone demethylase (show MBD2 Antibodies) that regulates neural differentiation through FGF4 (show FGF4 Antibodies).
The KIAA1718, a PHF2/PHF8 (show PHF2 Antibodies) subfamily member, possesses histone demethylase (show MBD2 Antibodies) activity specific for H3K9 and H3K27, transcriptionally repressive histone marks.
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate (By similarity).
histone lysine demethylase JHDM1D
, jmjC domain-containing histone demethylation protein 1D
, jumonji C domain-containing histone demethylase 1 homolog D
, lysine-specific demethylase 7