JHDM1D antibody (AA 290-316)

Catalog No. ABIN651309

Product Details anti-JHDM1D Antibody

Target: JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

Binding Specificity: AA 290-316

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JHDM1D antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JHDM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the Central region of human JHDM1D.

Clone: RB26200

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:100. IHC-P: 1:100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for JHDM1D

Target: JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

Alternative Name: JHDM1D (JHDM1D Products)

Synonyms: A630082K20Rik antibody, BB041802 antibody, ENSMUSG00000073143 antibody, Kdm7a antibody, mKIAA1718 antibody, KDM7A antibody, DrKDM7b antibody, im:7141664 antibody, Jhdm1d antibody, JHDM1D antibody, jhdm1d antibody, kdm7 antibody, kdm7a antibody, lysine (K)-specific demethylase 7A antibody, lysine demethylase 7A antibody, lysine (K)-specific demethylase 7Ab antibody, lysine (K)-specific demethylase 7A L homeolog antibody, Kdm7a antibody, KDM7A antibody, kdm7ab antibody, kdm7a.L antibody

Background: JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.

Molecular Weight: 106557

Gene ID: 80853

NCBI Accession: NP_085150

UniProt: Q6ZMT4