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JHDM1D Products

(Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

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Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate (By similarity).

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Featured JHDM1D Categories

JHDM1D Antibodies

High quality antibodies with extensive validation data.

Recommended JHDM1D Antibodies

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Reactivity Human
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Cat. No. ABIN651309
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Cat. No. ABIN7251559
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Reactivity Human
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Cat. No. ABIN7258046
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Recommended JHDM1D Proteins

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Source
Validations
Cat. No.
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Reactivity Human
Source Insect Cells
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Cat. No. ABIN3093283
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
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Cat. No. ABIN3135109
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Latest Publications for our JHDM1D products

Luo, Pei, Li, Gu: "Decreased expression of JHDMID in placenta is associated with preeclampsia through HLA-G." in: Journal of human hypertension, Vol. 32, Issue 6, pp. 448-454, (2018) (PubMed).

Synonyms and alternative names related to JHDM1D

lysine (K)-specific demethylase 7A (Kdm7a), lysine demethylase 7A (KDM7A), lysine (K)-specific demethylase 7Ab (kdm7ab), lysine demethylase 7A (Kdm7a), lysine (K)-specific demethylase 7A L homeolog (kdm7a.L), A630082K20Rik, BB041802, DrKDM7b, ENSMUSG00000073143, im:7141664, Jhdm1d, JHDM1D, jhdm1d, kdm7, Kdm7a, KDM7A, kdm7a, mKIAA1718

Protein level used designations for JHDM1D

  • jmjC domain-containing histone demethylation protein 1D
  • lysine-specific demethylase 7
  • histone lysine demethylase JHDM1D
  • jumonji C domain-containing histone demethylase 1 homolog D
  • JmjC domain-containing histone demethylation protein 1D-B
  • kdm7b
  • lysine-specific demethylase 7B
  • jumonji C domain containing histone demethylase 1 homolog D
  • lysine-specific demethylase 7A
  • jumonji C domain containing histone demethylase 1
  • lysine (K)-specific demethylase 7A
  • lysine (K)-specific demethylase 7A L homeolog
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