anti-Jun B Proto-Oncogene (JUNB) Antibodies

Transcription factor involved in regulating gene activity following the primary growth factor response. Additionally we are shipping JUNB Kits (12) and JUNB Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
JUNB 3726 P17275
JUNB 24517 P24898
JUNB 16477 P09450
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Top anti-JUNB Antibodies at antibodies-online.com

Showing 10 out of 300 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-JUNB Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Transfected 293T 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-JunB antibody, Western blotting All lanes: Anti JunB  at 0.5ug/ml Lane 1: Human Placenta Tissue Lysate at 50ug Lane 2: Rat Spleen Tissue Lysate at 50ug Lane 3: JURKAT Whole Cell Lysate at 40ug Lane 4: HELA Whole Cell Lysate at 40ug Predicted bind size: 36KD Observed bind size: 36KD 100 μg 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-JUNB Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  Transfected 293T Rabbit Anti-JUNB Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6269896 at 1/100 staining mouse lung tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269896 at 1/100 staining rat lung tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6269898 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269898 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$450.00
Details
Cow Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of JUNB staining in HEK293 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of JUNB staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
$487.50
Details
Cow Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of JUNB (pS259) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of JUNB (pS259) expression in HeLa (A), MCF7 (B) whole cell lysates. 200 μL 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Jun-B Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the JUNB antibody detected the JUNB protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of JUNB staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of JUNB expression in MCF7 (A), Hela (B), RAW264.7 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details

Top referenced anti-JUNB Antibodies

  1. Human Polyclonal JUNB Primary Antibody for IF, IHC (p) - ABIN6652447 : Bockmeyer, Kern, Forstmeier, Lovric, Modde, Agustian, Steffens, Birschmann, Traeder, Dämmrich, Schwarz, Kreipe, Bröcker, Becker: Arteriolar vascular smooth muscle cell differentiation in benign nephrosclerosis. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal JUNB Primary Antibody for IF, IHC - ABIN361924 : Narayanan, Srinivas, Peterson, Ramachandran, Hao, Thimmapaya, Scherer, George: Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal JUNB Primary Antibody for IHC, WB - ABIN361926 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal JUNB Primary Antibody for IHC, IP - ABIN6711807 : Xie, Feng, Su, Dong, Wu, Meng, Qu, Shou: Transcriptional regulation of PES1 expression by c-Jun in colon cancer. in PLoS ONE 2013 (PubMed)

  5. Cow (Bovine) Polyclonal JUNB Primary Antibody for IHC, WB - ABIN2780413 : Trøen, Nygaard, Jenssen, Ikonomou, Tierens, Matutes, Gruszka-Westwood, Catovsky, Myklebost, Lauritzsen, Hovig, Delabie: Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma. in The Journal of molecular diagnostics : JMD 2004 (PubMed)

More Antibodies against JUNB Interaction Partners

Human Jun B Proto-Oncogene (JUNB) interaction partners

  1. JUNB governs a feed-forward network of TGFB signaling that aggravates breast cancer invasion.

  2. MVIH and Jun-B have a synergistic effect on the regulation of angiogenesis and cell proliferation.

  3. IL-6-induced JunB expression contributes to epithelial-mesenchymal transition changes in uveal melanoma cells.

  4. LINC00657 might be involved in regulating esophageal squamous cell carcinoma (ESCC's) response to radiation; and it functioned as an oncogene in ESCC by targeting miR-615-3p and JunB.

  5. It has been shown that the AP-1 family member JunB and retinoic acid receptor alpha (RARa) mediate catalase transcriptional activation and repression, respectively, by controlling chromatin remodeling through a histone deacetylases-dependent mechanism.

  6. JunB neddylation mediated by Itch promotes its ubiquitination-dependent degradation.

  7. a specific role for AP-1/JunB in multiple myeloma cell proliferation, survival and drug resistance.

  8. BATF/JUN-B and BATF/C-JUN complexes play important roles in OA cartilage destruction through regulating anabolic and catabolic gene expression in chondrocytes.

  9. VEGF-induced endothelial migration is mediated primarily by induction of JunB whereas the promotion of endothelial proliferation by VEGF is mediated by JunB-independent AP-1 family members.

  10. Results suggested that JunB could play an important role in promoting cell invasion, migration and distant metastasis in head and neck squamous cell carcinoma via pathways other than epithelial-to-mesenchymal transition.

  11. Highly recurrent mutation of JUNB is associated with nodular lymphocyte predominant Hodgkin lymphoma.

  12. ETS2, HNF4A and JUNB are synergistic master regulators of epithelial-to-mesenchymal transition in cancer.

  13. CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.

  14. PDK1 functions as a tumor promoter in human gallbladder cancer by upregulating JunB, promoting epithelial mesenchymal transformation, and cell migration.

  15. Our findings demonstrate that miRNA-149* may serve as an oncogenic regulator in T-cell acute lymphoblastic leukemia by negatively regulating JunB

  16. The MAPK pathway plays a primary role in the control of JUNB gene expression.

  17. JunB is likely to be a key target of c-Abl in expression of p21 in Adriamycin-induced DDR.

  18. Caveolin 2 disengages repressed Egr-1 and JunB promoters from lamin A/C through disassembly of H3K9me3 in the inner nuclear membrane.

  19. JunB expression was significantly increased while cyclin-D1 expression was significantly down-regulated in pre-eclampsia relative to control placental mesenchymal stromal cells.

  20. findings uncover the oncogenic role of the JUNB/CD30 axis and its potential as therapeutic target in ALK+ ALCL.

Zebrafish Jun B Proto-Oncogene (JUNB) interaction partners

  1. Data demonstrate for the first time an essential role of JunB-CBFbeta signaling for maintaining sarcomere architecture and function.

Xenopus laevis Jun B Proto-Oncogene (JUNB) interaction partners

  1. JunB is a regulator of tail organization possibly through integration of several morphogen signaling pathways.

Cow (Bovine) Jun B Proto-Oncogene (JUNB) interaction partners

  1. The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 DNA-binding activity and expression of several transcriptions factors in breast cancer cells.

Mouse (Murine) Jun B Proto-Oncogene (JUNB) interaction partners

  1. JunB is a critical regulator of IRF4-dependent regulatory T cell effector programs, highlighting important functions for AP-1 in regulatory T cell-mediated immune homeostasis.

  2. JunB has an essential role in IL-23-dependent pathogenicity of Th17 cells

  3. Data show that JunB is a nonredundant regulator of transcriptional programs that support Th17 cell identity and restrain alternative Th1 and Treg cell fates.

  4. the present data demonstrates for the first time that JunB plays an important role in the formation of embryonic vascular networks.

  5. BATF/JUN-B and BATF/C-JUN complexes play important roles in OA cartilage destruction through regulating anabolic and catabolic gene expression in chondrocytes.

  6. JUNB is a significant modulator of both classical and alternative macrophage activation.

  7. Study shows that myeloid deletion of JUNB dampens immune polarization and reshapes disease outcomes during infection with both P. berghei and N. brasiliensis by limiting type 1 and type 2 responses, respectively. Thus, JUNB is an important regulator of myeloid responses to both type 1 and type 2 infections in vivo.

  8. Loss of JunB expression led to increased proliferation and decreased senescence, likely owing to decreased p16(Ink4a) and p21(CIP1) in epithelial cells.

  9. JunB and c-Jun expression in post-mitotic oligodendrocytes is mostly dispensable for the maintainance of white matter tracts throughout adult life, even under demyelinating conditions.

  10. JunB controls epidermal growth, barrier formation, and proinflammatory responses through direct and indirect mechanisms, pinpointing SQSTM1 as a key mediator of JunB suppression of NF-kappaB-dependent inflammation

  11. our results suggest a functional cooperation between NFAT1 and JunB in mediating IL-31 gene expression in CD4(+) T cells

  12. an important role of the A2B receptor-dependent upregulation of JunB in VEGF production and possibly other AP-1-regulated events.

  13. In experimental hepatitis, the absence of JUNB in immune cells decreased IFN-gamma expression and secretion from NK & NKT cells, leading to reduced STAT1 pathway activation.

  14. The results show that the junb gene is organized in a nuclear chromatin loop bringing into close spatial proximity the upstream promoter region and the downstream enhancer and that this configuration permits immediate RNA Pol II release on the junb body on binding of LPS-activated NF-kappaB to the enhancer.

  15. Data indicate that the C-terminal JunB caspase cleavage product functions as a potent inhibitor of AP-1-dependent transcription.

  16. Data suggest that JunB contributes to Id2 repression and provides important input in setting the transcriptional program of the EMT and profibrotic responses to TGF-beta.

  17. Wwp1 induces JunB ubiquitination and degradation.

  18. investigation of role of JunB: growth retardation of JunB-deficient mice correlates with strongly reduced fat mass (and is also associated with high lethality); in white adipose tissue, TNFalpha is up-regulated and perilipin is down-regulated

  19. T cell receptor signaling together with TGF-beta/IL-2 stimulation cooperatively enhance Foxp3 gene expression by maintaining accessible chromatin structure and by actively recruiting key transcription factors JunB and c-Rel.

  20. JunB is important not only in dividing populations but also in adult muscle, where it is required for the maintenance of muscle size and can induce rapid hypertrophy and block atrophy.

JUNB Antigen Profile

Protein Summary

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGATCA-3'.

Gene names and symbols associated with JUNB

  • JunB proto-oncogene, AP-1 transcription factor subunit (JUNB) antibody
  • JunB proto-oncogene, AP-1 transcription factor subunit (Junb) antibody
  • JunB proto-oncogene, AP-1 transcription factor subunit a (junba) antibody
  • jun B proto-oncogene L homeolog (junb.L) antibody
  • jun B proto-oncogene (junb) antibody
  • jun B proto-oncogene S homeolog (junb.S) antibody
  • jun B proto-oncogene (Junb) antibody
  • JunB proto-oncogene, AP-1 transcription factor subunit b (junbb) antibody
  • AP-1 antibody
  • JUNB antibody
  • junbl antibody
  • MGC81322 antibody
  • wu:cegs2778 antibody
  • wu:fa92h07 antibody
  • wu:fa95h09 antibody
  • wu:fj44e11 antibody
  • wu:fj68b07 antibody
  • wu:fq24h03 antibody
  • zgc:63933 antibody
  • zgc:64066 antibody

Protein level used designations for JUNB

activator protein 1 , transcription factor jun-B , Jun-B oncogene , jun B proto-oncogene , jun-B proto-oncogene , myD21 , JunB proto-oncogene, AP-1 transcription factor subunit b , jun B proto-oncogene b , jun B proto-oncogene, like

GENE ID SPECIES
3726 Homo sapiens
24517 Rattus norvegicus
407086 Danio rerio
432129 Xenopus laevis
443117 Ovis aries
468739 Pan troglodytes
514246 Bos taurus
733713 Xenopus (Silurana) tropicalis
779417 Xenopus laevis
16477 Mus musculus
100716068 Cavia porcellus
100146801 Equus caballus
100856456 Canis lupus familiaris
102181201 Capra hircus
336038 Danio rerio
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