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LANCL1 encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. Additionally we are shipping LANCL1 Proteins (10) and and many more products for this protein.
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Human Polyclonal LANCL1 Primary Antibody for ELISA, WB - ABIN564481
Zeng, van der Donk, Chen: Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. in Molecular biology of the cell 2014
Show all 2 Pubmed References
Very similar concentrations of lanthionine ketimine (0.5-2.5 nmol/g tissue) were found in LanCL1 knock-out, LanCL1/LanCL2/LanCL3 triple-knock-out and wild type (WT) mouse brains, suggesting that LanCL proteins are not involved in lanthionine biosynthesis.
Loss of LanCL1 causes progressive oxidative damage and neuronal death. LanCL1 transgene protects neurons from oxidative stress.
Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense.
LanC-like protein 1 expression in rat testes was initiated already in pachytene spermatocytes in stage IX, but otherwise similar to mouse.
the crystal structures of human LanCL1, both free of and complexed with glutathione, revealing glutathione binding to a zinc ion at the putative active site formed by conserved GxxG motifs
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
LanC lantibiotic synthetase component C-like 1 (bacterial)
, lanthionine synthetase C-like protein 1
, LanC lantibiotic synthetase component C-like 1
, 40 kDa erythrocyte membrane protein
, G protein-coupled receptor 69
, G protein-coupled receptor 69A
, lanC-like protein 1
, LanC (bacterial lantibiotic synthetase component C)-like 1
, LanC (bacterial lantibiotic synthetase component)
, LanC-like 1
, LanC-like 1(bacterial)
, lanC (bacterial lantibiotic synthetase component C)-like 1