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The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. Additionally we are shipping Leiomodin 1 Antibodies (33) and Leiomodin 1 Kits (2) and many more products for this protein.
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Key role for miR (show MLXIP Proteins)-214 in modulation of MEF2C (show MEF2C Proteins)-MYOCD-LMOD1 signaling.
LMOD1, SYNPO2, PDLIM7 (show PDLIM7 Proteins), PLN (show PLN Proteins), and SYNM (show SYNM Proteins) down-regulation reflect the altered phenotype of smooth muscle cells in vascular disease and could be early sensitive markers of SMC (show DYM Proteins) dedifferentiation.
Lmod1 is a new SMC-restricted SRF/MYOCD target gene.
Lmod1 is a component of the smooth muscle contractile apparatus extractable by high salt, not a transmembrane protein as previously predicted.
Lmod1, formerly the 64kD human autoantigen D1, is expressed in smooth muscle and striated extraocular slow muscle fibers, colocalized with myosin in the contractile apparatus. Protein levels are unaltered by hyperthyroidism.
Lmod1 is a member of the Tropomodulin family of actin binding proteins, and is most highly expressed in smooth muscle.
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy.
64 kDa autoantigen 1D
, 64 kDa autoantigen 1D3
, 64 kDa autoantigen D1
, leimodin 1 (smooth muscle)
, leiomodin, muscle form
, smooth muscle leiomodin
, thyroid and eye muscle autoantigen D1 (64kD)
, thyroid-associated ophthalmopathy autoantigen