anti-Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) Antibodies

The protein encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. Additionally we are shipping LDOC1 Proteins (11) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LDOC1 23641 O95751
LDOC1 367956  
LDOC1 434784 Q7TPY9
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Top anti-LDOC1 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-LDOC1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate Immunohistochemistry with Human Thyroid lysate tissue at an antibody concentration of 5.0ug/ml using anti-LDOC1 antibody 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with LDOC1 antibody ABIN462213 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Breast (formalin-fixed, paraffin-embedded) stained with LDOC1 antibody ABIN462213 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 100 μL 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of LDOC1 using COLO205 whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-LDOC1/BCUR1 Polyclonal Antibody, Unconjugated (ABIN717836) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Available
$363.46
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC, ELISA   100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Mouse Un-conjugated DB   50 μg 11 to 14 Days
$493.17
Details
Human Mouse Un-conjugated WB   100 μL 11 to 14 Days
$522.50
Details

Top referenced anti-LDOC1 Antibodies

  1. Human Polyclonal LDOC1 Primary Antibody for IHC, IHC (p) - ABIN4894466 : Salemi, Barone, La Vignera, Condorelli, Recupero, Galia, Fraggetta, Aiello, Pepe, Castiglione, Vicari, Calogero: Leucine zipper, down regulated in cancer-1 gene expression in prostate cancer. in Oncology letters 2016 (PubMed)

More Antibodies against LDOC1 Interaction Partners

Human Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) interaction partners

  1. LDOC1 is a tumor suppressor in Colorectal cancer (CRC) and it inhibits cell proliferation and promotes cell apoptosis. Additionally, it inhibits CRC cell metastasis by downregulating the Wnt/betacatenin signaling pathway.

  2. that epigenetic silencing of LDOC1 in high-risk Group A ependymoma regulates tumor biology and drives inflammatory immune phenotype

  3. GNL3L-LDOC1 interplay regulates cell proliferation through the modulation of NF-kappaB pathway during tumorigenesis.

  4. These finding of this study suggested that the hypothesize that LDOC1 gene upregulation may play a role in the spermatogenesis derangement observed in patients with Klinefelter Syndrome.

  5. data show that LDOC1 is a tumor suppressor in osteosarcoma, and that it regulates metastasis of osteosarcoma cells. Furthermore, LDOC1 might be a valuable prognostic marker in osteosarcomas.

  6. Cigarette smoke-induced promoter methylation may contribute to LDOC1 downregulation, thereby conferring oncogenic features to oral cells.

  7. LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-kappaB activation in papillary thyroid carcinoma

  8. It has potential roles in apoptosis of well differentiated carcinoma without metastases and in neurodegeneration of Alzheimer's disease.

  9. Silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.

  10. Silencing of BEX1 and LDOC1 by promoter hypermethylation might represent a critical event in the molecular pathogenesis of oral squamous cell carcinoma (OSCC) and the male predominance of OSCC occurrence.

  11. Letter/Case Report: LDOC1/PARP1 are down-regulated in melanoma with repeated in-transit metastases.

  12. The aim of this study was to evaluate the possible differential expression of LDOC1 mRNA in leucocytes of peripheral blood of Down's syndrome subjects. compared with the normal population.

  13. Over expression of LDOC1 may explain the clinical manifestation found in patients with cryptochidism and Digeorge anomaly.

  14. LDOC1 is dramatically down-regulated in mutated chronic lymphocytic leukemia cases compared with unmutated cases, and have identified a new splice variant, LDOC1S

  15. These observations suggest that LDOC1 is a novel regulator of NF-kappaB that can affect the PMA or TNF-alpha-mediated pathway to apoptosis through inhibition of NF-kappaB activation in BxPC3 pancreatic cancer cells.

  16. MZF-1 was revealed to interact with LDOC1 and enhance the activity of LDOC1 for inducing apoptosis

LDOC1 Antigen Profile

Protein Summary

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Gene names and symbols associated with LDOC1

  • LDOC1, regulator of NFKB signaling (LDOC1) antibody
  • LDOC1, regulator of NFKB signaling (Ldoc1) antibody
  • regulator of NFKB signaling (Ldoc1) antibody
  • BCUR1 antibody
  • Gm366 antibody
  • LDOC1 antibody
  • Mar7 antibody
  • Mart7 antibody
  • RGD1565644 antibody

Protein level used designations for LDOC1

breast cancer, up-regulated 1 , leucine zipper protein down-regulated in cancer cells , protein LDOC1 , leucine zipper, down-regulated in cancer 1 , Protein LDOC1 , leucine zipper down-regulated in cancer 1

GENE ID SPECIES
23641 Homo sapiens
367956 Rattus norvegicus
434784 Mus musculus
616591 Bos taurus
696902 Macaca mulatta
100345630 Oryctolagus cuniculus
100969658 Pan paniscus
100855971 Canis lupus familiaris
100055774 Equus caballus
100731711 Cavia porcellus
100525445 Sus scrofa
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