LDOC1 antibody (N-Term)

Catalog No. ABIN2780876

This Rabbit Polyclonal antibody specifically detects LDOC1 in IHC and WB. It exhibits reactivity toward Human, Rat, Cow, Dog, Guinea Pig, Rabbit and Horse.

Quick Overview for LDOC1 antibody (N-Term) (ABIN2780876)

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDOC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-LDOC1 Antibody

Binding Specificity: N-Term

Purpose: LDOC1 Antibody - N-terminal region

Sequence: MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38983-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LDOC1

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Alternative Name: LDOC1

Background:

Background Information: LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Gene Name: Leucine zipper, down-regulated in cancer 1

Alternative Symbols: Mar7, RTL7, BCUR1, Mart7, SIRH7

Protein Name: Protein LDOC1

Molecular Weight: 17kDa

Gene ID: 23641

NCBI Accession: NP_036449

UniProt: O95751