Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Additionally we are shipping LZTS2 Proteins (6) and and many more products for this protein.
Showing 10 out of 52 products:
Lzts2 regulates gastrula CE movements, dorsoventral patterning, and midline convergence and specification of organ precursors through interaction with and the export of nuclear beta-catenins in zebrafish.
LZTS2 promoter hypermethylation is associated with laryngeal squamous cell carcinoma.
LZTS2 could inhibit cell proliferation and cell cycle transition at the G1/S phase and was implicated in the regulation of proteins associated with the canonical Wnt pathway, including GSK3B and beta-catenin through inactivating the Akt pathway.
deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.
LZTS2 is a beta-catenin-interacting protein and modulates beta-catenin signaling and localization
The reciprocal crosstalk between beta-catenin/Tcf pathway and NF-kappaB signaling in hMSCs is mediated through the regulation of lzts2 expression.
LAPSER1 C terminal domain inhibits katanin(p80/p60)-mediated microtubule severing in vitro.
The data demonstrate the significance of simultaneous Pten and Lzts2 deletion in oncogenic transformation in prostate cells and implicates a new mechanism for the dysregulation of Wnt/beta-catenin signaling in prostate tumorigenesis.
a critical role of LZTS2 in renal development and implicate LZTS2 as a critical regulator of beta-catenin-mediated nephrogenesis.
Members of the ProSAP/Shank family and LAPSER1 not only play a role in postsynaptic density formation and plasticity, but also during embryonic development.
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin (By similarity).
leucine zipper putative tumor suppressor 2 homolog
, Protein lapser1
, leucine zipper, putative tumor suppressor 2
, leucine zipper putative tumor suppressor 2-like
, leucine zipper putative tumor suppressor 2
, putative tumor suppressor LAPSER1
, Protein LAPSER1
, protein lapser1