LZTS2 antibody (AA 470-669)

Catalog No. ABIN7268227

This Rabbit Polyclonal antibody specifically detects LZTS2 in WB. It exhibits reactivity toward Human.

Quick Overview for LZTS2 antibody (AA 470-669) (ABIN7268227)

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LZTS2 Antibody

Binding Specificity: AA 470-669

Purpose: LZTS2 Rabbit pAb

Sequence: ELVALRVALR EARATLRVSE GRARGLQEAA RARELELEAC SQELQRHRQE AEQLREKAGQ LDAEAAGLRE PPVPPATADP FLLAESDEAK VQRAAAGVGG SLRAQVERLR VELQRERRRG EEQRDSFEGE RLAWQAEKEQ VIRYQKQLQH NYIQMYRRNR QLEQELQQLS LELEARELAD LGLAEQAPCI CLEEITATEI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-669 of human LZTS2 (NP_115805.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LZTS2

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Alternative Name: LZTS2

Background: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.,LZTS2,LAPSER1,LZTS2

Molecular Weight: 72kDa

Gene ID: 84445

UniProt: Q9BRK4