anti-Leucyl-tRNA Synthetase 2, Mitochondrial (LARS2) Antibodies

LARS2 encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LARS2 23395 Q15031
LARS2 363172  
LARS2 102436 Q8VDC0
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Top anti-LARS2 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Molt-4 , 7.5% SDS PAGE antibody diluted at 1:3000 ICC/IF Image Immunofluorescence analysis of methanol-fixed A431, using LARS2, antibody at 1:200 dilution. 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated EIA, WB Flow cytometric analysis of K562 cells using LARS2 Antibody (Center) Cat.-No AP52445PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of LARS2 Antibody (Center) in CEM cell line lysates (35ug/lane). This demonstrates the LARS2 antibody detected the LARS2 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated FACS, WB LARS2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the LARS2 antibody detected the LARS2 protein (arrow). LARS2 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image LARS2 antibody [N1N2], N-term detects LARS2 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37℃ for 30 min. Green: LARS2 protein stained by LARS2 antibody [N1N2], N-term , diluted at 1:500. Blue: Hoechst 33343 staining. IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using LARS2, antibody at 1:500 dilution. 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis in CEM cell line lysates (35ug/lane). Flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL 2 to 3 Days
$515.63
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.89 KDa) . 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated WB Western Blot analysis of LARS2 expression in transfected 293T cell line by LARS2 MaxPab polyclonal antibody.Lane 1: LARS2 transfected lysate(102.00 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated DB, ICC   50 μg 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB   100 μL 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB   100 μL 11 to 14 Days
$537.17
Details

Top referenced anti-LARS2 Antibodies

  1. Human Polyclonal LARS2 Primary Antibody for ICC, IF - ABIN4330339 : Perli, Giordano, Pisano, Montanari, Campese, Reyes, Ghezzi, Nasca, Tuppen, Orlandi, Di Micco, Poser, Taylor, Colotti, Francisci, Morea, Frontali, Zeviani, dAmati: The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells. in EMBO molecular medicine 2014 (PubMed)

More Antibodies against LARS2 Interaction Partners

Human Leucyl-tRNA Synthetase 2, Mitochondrial (LARS2) interaction partners

  1. We report novel associations between methylation at MSI2 and LARS2 and obesity-related traits. These results provide further insight into mechanisms underlying obesity-related traits, which can enable identification of new biomarkers in obesity-related chronic diseases.

  2. We concluded that Perrault syndrome patients with LARS2 mutations are at risk for neurologic problems, despite previous notions otherwise.

  3. IARS2 knockdown inhibits proliferation, suppresses colony formation, and causes cell cycle arrest in AGS cells.

  4. ere we present eight families affected by Perrault syndrome. In five families we identified novel or previously reported variants in HSD17B4, LARS2, CLPP and C10orf2

  5. This represents the first independent replication of the involvement of LARS2 mutations in Perrault syndrome, contributing valuable information for the further understanding of this disease

  6. analysis of the CP1 domain in human mitochondrial leucyl-tRNA synthetase

  7. Leucyl tRNA synthetase is able to partially rescue defects caused by mutations in non-cognate itochondrial-tRNAs.

  8. Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome.

  9. No evidence to support previous data indicating a role in type 2 diabetes susceptibility in humans with LARS2 single nucleotide polymorphisms

  10. The alteration of aminoacylation tRNA(Leu(UUR)) caused by the A3243G mutation led to mitochondrial translational defects and thereby reduced the aminoacylated efficiencies of tRNA(Leu(UUR)) as well as tRNA(Ala) and tRNA(Met).

  11. Upregulation of LARS2 is a hallmark of 324A>G mutation. The accumulation of 3243A>G mutation in the brain may have a pathophysiologic role in bipolar disorder and schizophrenia.

  12. In this study, we provide evidence that the LARS2 gene may represent a novel type 2 diabetes susceptibility gene.

  13. There was investigated whether overexpression of human mitochondrial LeuRS suppressed translation and respiratory chain defects associated with the pathogenic A3243G mutation in human cells.

  14. data indicate that inactivation of LARS2 by both genetic and epigenetic mechanisms may be a common and important event in the carcinogenesis of nasopharyngeal carcinoma

LARS2 Antigen Profile

Protein Summary

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.

Gene names and symbols associated with LARS2

  • leucyl-tRNA synthetase 2, mitochondrial (LARS2) antibody
  • leucyl-tRNA synthetase 2 L homeolog (lars2.L) antibody
  • probable leucine--tRNA ligase, mitochondrial (LOC100163590) antibody
  • leucyl-tRNA synthetase 2 (lars2) antibody
  • leucyl-tRNA synthetase 2, mitochondrial (lars2) antibody
  • leucyl-tRNA synthetase 2, mitochondrial (Lars2) antibody
  • leucyl-tRNA synthetase, mitochondrial (Lars2) antibody
  • AI035546 antibody
  • Kiaa0028 antibody
  • LARS2 antibody
  • LEURS antibody
  • MGC80460 antibody
  • PRLTS4 antibody

Protein level used designations for LARS2

leucyl-tRNA synthetase 2, mitochondrial , probable leucyl-tRNA synthetase, mitochondrial , Probable leucyl-tRNA synthetase, mitochondrial , leuRS , leucine--tRNA ligase , probable leucine--tRNA ligase, mitochondrial , probable leucyl-tRNA synthetase, mitochondrial-like , leucine tRNA ligase 2, mitochondrial , leucine tRNA ligase 2, mitocondrial , leucine translase , leucyl-tRNA synthetase, mitochondrial

GENE ID SPECIES
420702 Gallus gallus
443989 Xenopus laevis
476652 Canis lupus familiaris
504609 Bos taurus
714224 Macaca mulatta
739246 Pan troglodytes
100082885 Ornithorhynchus anatinus
100163590 Acyrthosiphon pisum
100174294 Pongo abelii
100358356 Oryctolagus cuniculus
100379697 Xenopus (Silurana) tropicalis
100484574 Ailuropoda melanoleuca
100540484 Meleagris gallopavo
100556212 Anolis carolinensis
23395 Homo sapiens
363172 Rattus norvegicus
102436 Mus musculus
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