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LAPTM4A encodes a protein that has four predicted transmembrane domains.
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hOCT2 (show SLC22A2 Antibodies) interacts with LAPTM4A in lysosomes and late endosomes and regulates endocytotic recruitment.
The results suggest that while some requisites of LAPTM5 lysosomal sorting are conserved among LAPTM4 proteins, LAPTM4a and LAPTM4b have also developed distinct sorting requirements.
LAPTM4 alpha is the first example of a membrane protein that requires two tandemly arranged tyrosine-based sorting signals for efficient localization in lysosomes and endosomes.
This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined\; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes.
lysosomal-associated protein transmembrane 4 alpha
, lysosomal-associated transmembrane protein 4A
, golgi 4-transmembrane-spanning transporter MTP
, membrane nucleoside transporter
, lysosomal-associated protein transmembrane 4A
, lysosomal protein transmembrane 4 alpha a
, golgi 4-transmembrane spanning transporter
, golgi 4-transmembrane-spanning transporter
, membrane transporter protein
, transporter protein