anti-MAP/microtubule Affinity-Regulating Kinase 4 (MARK4) Antibodies

MARK4 encodes a member of the microtubule affinity-regulating kinase family. Additionally we are shipping MARK4 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARK4 57787 Q96L34
MARK4 232944 Q8CIP4
MARK4 680407  
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Top anti-MARK4 Antibodies at antibodies-online.com

Showing 10 out of 128 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184722 (0.5µg/ml) staining of human prostate lysate (35µg protein in RIPA buffer). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.62
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MARK4 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using MARK4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-MARK4 Pab (ABIN391222) in mouse liver tissue lysate (35 µg/lane). MARK4(arrow) was detected using the purified polyclonal antibody (1:40dilution). Western blot analysis of MARK4 (arrow) using rabbit polyclonal hMARK4-R626 Antibody (ABIN391222).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MARK4 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF ABIN6266961 staining MCF-7 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, WB (LEFT)Western blot analysis of anti-MARK4 Pab in mouse liver tissue lysate (35ug/lane). MARK4(arrow) was detected using the purified Pab (1:40dilution). (RIGHT)Western blot analysis of MARK4 (arrow) using rabbit polyclonal hMARK4-R626 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MARK4 gene (Lane 2) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA 50 μg Log in to see 12 to 14 Days
$685.40
Details
Human Goat Un-conjugated WB   0.1 mg Log in to see 8 to 11 Days
$462.00
Details

Top referenced anti-MARK4 Antibodies

  1. Human Polyclonal MARK4 Primary Antibody for ELISA, WB - ABIN249489 : Kato, Satoh, Okabe, Kitahara, Ono, Kihara, Tanaka, Tsunoda, Yamaoka, Nakamura, Furukawa: Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. in Neoplasia (New York, N.Y.) 2001 (PubMed)

More Antibodies against MARK4 Interaction Partners

Human MAP/microtubule Affinity-Regulating Kinase 4 (MARK4) interaction partners

  1. data demonstrate that miR (show MLXIP Antibodies)-515-5p dramatically inhibits cell migration by directly down-regulating MARK4 expression in two different cancer types

  2. Our results show that MARK4 acts as a negative regulator of the Hippo kinase cassette to promote YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activity and that loss of MARK4 restrains the tumorigenic properties of breast cancer cells.

  3. Atypical PKC (show PRRT2 Antibodies) phosphorylates serine-threonine residues of MARK4.

  4. Suggest role for polypyrimidine-tract binding protein (show PTBP1 Antibodies) in regulating alternative splicing of MARK4 in gliomas.

  5. MARK4 is a key component in the regulation of microtubule dynamics and has major role in cell cycle progression, particularly at the G1/S transition.

  6. Molecular dynamic simulation data predicted the three dimensional structure for the kinase domain of MARK4 and its structural properties.

  7. A strong and significant elevation of MARK4 expression and MARK4-tau interactions in AD brains correlates with the Braak stages of the disease, suggesting that the MARK4-tau interactions are of functional importance in the progression of AD.

  8. MARK4 is a critical positive regulator of early steps in ciliogenesis.

  9. MARK4 is a new negative regulator of mTORC1

  10. The balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis.

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 4 (MARK4) interaction partners

  1. PPARgamma (show PPARG Antibodies) interacted with Mark4 and inhibited the stimulating effect of Mark4 on oxidative stress and inflammation.

  2. MARK4 is a critical positive regulator of early steps in ciliogenesis.

  3. data indicate a key role of MARK4 in energy metabolism, implicating the kinase as a novel drug target for the treatment of obesity and type 2 diabetes.

  4. The balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis.

  5. MARK4 is a functional protein kinase (show CDK7 Antibodies) which specifically phosphorylates a cognate peptide substrate for the AMP (show TMPRSS5 Antibodies)-kinase family. On overexpression in heterologous cells functional wild-type protein, but not its kinase-dead mutant, decreased cell viability

MARK4 Antigen Profile

Protein Summary

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with MARK4

  • microtubule affinity regulating kinase 4 (MARK4) antibody
  • MAP/microtubule affinity regulating kinase 4 (Mark4) antibody
  • microtubule affinity regulating kinase 4 (Mark4) antibody
  • 2410090P21Rik antibody
  • C79806 antibody
  • MARK4 antibody
  • MARK4L antibody
  • MARK4S antibody
  • Markl1 antibody
  • MARKL1L antibody
  • PAR-1D antibody

Protein level used designations for MARK4

MAP/microtubule affinity-regulating kinase 4 , MAP/microtubule affinity-regulating kinase like 1 , MARK4 serine/threonine protein kinase , MAP/microtubule affinity-regulating kinase 4L

GENE ID SPECIES
100070770 Equus caballus
456123 Pan troglodytes
57787 Homo sapiens
232944 Mus musculus
680407 Rattus norvegicus
484449 Canis lupus familiaris
525675 Bos taurus
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