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MARK4 Products

(MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Categories

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

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Featured MARK4 Categories

MARK4 Antibodies

High quality antibodies with extensive validation data.

MARK4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MARK4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN2706507
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN784580
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7191406
Quantity 100 μL
Datasheet Datasheet

Recommended MARK4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6219509
Quantity 96 tests
Datasheet Datasheet

Recommended MARK4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5570615
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093721
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136493
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MARK4 products

Lu, Murata-Kamiya, Saito, Hatakeyama: "Role of partitioning-defective 1/microtubule affinity-regulating kinases in the morphogenetic activity of Helicobacter pylori CagA." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 23024-36, (2009) (PubMed).

Trinczek, Brajenovic, Ebneth, Drewes: "MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes." in: The Journal of biological chemistry, Vol. 279, Issue 7, pp. 5915-23, (2004) (PubMed).

Schneider, Laage, von Ahsen, Fischer, Rossner, Scheek, Grünewald, Kuner, Weber, Krüger, Klaussner, Götz, Hiemisch, Newrzella, Martin-Villalba, Bach, Schwaninger: "Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4." in: Journal of neurochemistry, Vol. 88, Issue 5, pp. 1114-26, (2004) (PubMed).

Kato, Satoh, Okabe, Kitahara, Ono, Kihara, Tanaka, Tsunoda, Yamaoka, Nakamura, Furukawa: "Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis." in: Neoplasia (New York, N.Y.), Vol. 3, Issue 1, pp. 4-9, (2001) (PubMed).

Nagase, Nakayama, Nakajima, Kikuno, Ohara: "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 8, Issue 2, pp. 85-95, (2001) (PubMed).

Synonyms and alternative names related to MARK4

microtubule affinity regulating kinase 4 (MARK4), MAP/microtubule affinity regulating kinase 4 (Mark4), microtubule affinity regulating kinase 4 (Mark4), 2410090P21Rik, C79806, MARK4, MARK4L, MARK4S, MARKL1, Markl1, MARKL1L, PAR-1D

Protein level used designations for MARK4

  • MAP/microtubule affinity-regulating kinase 4
  • MAP/microtubule affinity-regulating kinase like 1
  • MARK4 serine/threonine protein kinase
  • MAP/microtubule affinity-regulating kinase 4L
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