anti-Macrophage Scavenger Receptor 1 (MSR1) Antibodies

MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. Additionally we are shipping Macrophage Scavenger Receptor 1 Kits (31) and Macrophage Scavenger Receptor 1 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MSR1 4481 P21757
MSR1 20288 P30204
MSR1 498638  
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Top anti-Macrophage Scavenger Receptor 1 Antibodies at antibodies-online.com

Showing 10 out of 220 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat Un-conjugated EIA, FACS, IHC (fro), IP, WB Staining of J774 cell line with RAT ANTI MOUSE CD204 (ABIN181780). 0.25 mg Log in to see 6 to 8 Days
$511.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MSR1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125] - Staining of human lung shows strong cytoplasmic positivity in macrophages. Western Blot: SR-AI/MSR Antibody [NBP1-88125] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 | Lane 2: Negative control (vector only transfected HEK293T lysate) | Lane 3: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Mouse Rat Biotin FACS Staining of mouse peritoneal macrophages with RAT ANTI MOUSE CD204: BIOTIN. ABIN181777 0.1 mg Log in to see 6 to 8 Days
$478.50
Details
Human Mouse PE FACS Detection of SR-AI/MSR in THP-1 Human Cell Line by Flow Cytometry. THP-1 human acute monocytic leukemia cell line activated with PMA and Ca2+ ionomycin was stained with Mouse Anti-Human SR-AI/MSR PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$352.56
Details
Mouse Rat FITC FACS   25 μg Log in to see 6 to 8 Days
$198.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of extracts of various cell lines, using MSR1 antibody. ABIN6276957 staining HepG2? cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Mouse Rat Un-conjugated EIA, Func, FACS, IHC (fro), IP, WB Staining of mouse peritoneal macrophages with RAT ANTI MOUSE CD204: LOW 0.5 mg Log in to see 6 to 8 Days
$632.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IF, WB Immunocytochemistry/Immunofluorescence: SR-AI/MSR Antibody [NBP1-00092] - The MSR antibody was tested in Raw cells at a 1:250 dilution against Dylight 488 (Green). Alpha-tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue), respectively. 0.1 mL Log in to see 7 to 9 Days
$488.73
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and human glioma tissue labeled with Anti-MSR1/CD204 Polyclonal Antibody, Unconjugated (ABIN872905) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human esophageal cancer labeled with Anti-MSR1/CD204 Polyclonal Antibody, Unconjugated (ABIN872905) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details

Top referenced anti-Macrophage Scavenger Receptor 1 Antibodies

  1. Human Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for FACS - ABIN4897783 : Tran, Ahern, Hodge, Holt, Dean, Reynolds, Hodge: Oxidative stress decreases functional airway mannose binding lectin in COPD. in PLoS ONE 2014 (PubMed)
    Show all 7 Pubmed References

  2. Catfish (Ictalurus) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for IHC (fro), FACS - ABIN2479175 : Brink: Quantitative vs qualitative research. in Nursing RSA = Verpleging RSA 1991 (PubMed)
    Show all 4 Pubmed References

  3. Catfish (Ictalurus) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for FACS - ABIN2479177 : Allred, Smart, Wilson: Estrogen receptor-alpha mediates gender differences in atherosclerosis induced by HIV protease inhibitors. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 Pubmed References

  4. Catfish (Ictalurus) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for FACS - ABIN2479183 : Anatelli, Mroz, Liu, Yang, Castano, Swietlik, Hamblin: Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection. in Molecular pharmaceutics 2006 (PubMed)
    Show all 4 Pubmed References

  5. Catfish (Ictalurus) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for Func, IHC (fro) - ABIN2479187 : Aid, Langenbach, Bosetti: Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2. in Journal of neuroinflammation 2008 (PubMed)
    Show all 4 Pubmed References

More Antibodies against Macrophage Scavenger Receptor 1 Interaction Partners

Human Macrophage Scavenger Receptor 1 (MSR1) interaction partners

  1. The expression of CD204 in tumor-associated macrophages is associated with the aggressiveness of lung adenocarcinoma.

  2. Decreased expression by OxLDL in PMA-differentiated THP-1 macrophages. Increased expression in plaque vs. nonplaque lesion areas in human carotid endarterectomy specimens (correlated with CD36 expression).

  3. Cytokine abnormality induced by SRA(+) cells playS an role in tissue injury, and platelet emboli or contraction band necrosis might have been the leading cause of death in our SUDI cases.

  4. TGM2 has a role in macrophage differentiation via mechanisms involving CD14 and SR-AI receptors.

  5. study demonstrates the elevated SR-A expression on cell surface contributes to increased susceptibility to Adenovirus serotype 5 (Ad5) infection into CD14+ monocytes; SR-A-mediated Ad5 entry, TLR3 signaling activation and acLDL accumulation in monocytes/ macrophages synergistically trigger the inflammatory responses and innate immunity against Ad5 infection

  6. SR-A1 expression in 136 human gliomas was positively correlated with tumor grade (P<0.01), but not prognosis or tumor recurrence

  7. The results reveal marked differences between afferent and efferent ymphatic endothelial cells and identify molecules on lymphatic vessels. Further characterizations of Siglec-1 (CD169) and macrophage scavenger receptor 1 (MSR1/CD204), show that they are discriminatively expressed on lymphatic endothelium of the subcapsular sinus but not on lymphatic vasculature of the lymphatic sinus

  8. High density of CD204(+) tumor-associated macrophages was associated with the aggressive behavior and worse survival of gastric cancer. Low density of CD204(+) TAMs was associated with infection of EBV, which may explain the favorable outcome of EBV-associated gastric carcinoma.

  9. SR-A1 suppresses lung cancer metastasis by downregulating SAA1 production in tumor-associated macrophages (TAM).

  10. PTX2 was identified PTX2 as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.

  11. we found that higher percentages of circulating CD14+CD204+, CD14+CD163+CD204+ M2-like monocytes were significantly associated with TNM stage, lymph node metastasis, and histological differentiation.

  12. Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO.

  13. Findings suggest that CD204+ Mphis might play detrimental protumoral roles and represent the predominant Mphi phenotype in human bladder cancer.

  14. The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.

  15. Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma

  16. miR-29a promotes scavenger receptor A expression by targeting QKI during monocyte-macrophage differentiation.

  17. Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta to SR-A, thereby promoting glial phagocytosis of Abeta oligomer in microglia.

  18. The truncating variant Arg293X in the gene encoding SRA-I/II was associated with reduced lung function and with increased risk of COPD among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase-3 E1I1 heterozygotes.

  19. monomeric collagen type I via CD204 induces phospho-Akt expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.

  20. High CD204 expression is an independent predictor for both overall and disease-free survival in pancreatic ductal adenocarcinoma.

Mouse (Murine) Macrophage Scavenger Receptor 1 (MSR1) interaction partners

  1. Custom-produced fluorescently labeled versions of MOG or MDA-modified MOG was used to study and quantify the uptake by different macrophage populations (especially anti-inflammatory M2-type macrophages) and to identify the responsible receptor, namely SRA. The SRA-mediated uptake of MDA-modified MOG is roughly tenfold more efficient compared to that of the native form.

  2. TMP upregulated the protein stability of ABCA1 without affecting ABCG1. Accordingly, TMP regulated the expression of SR-A, CD36, ABCA1 and ABCG1 in aortas of ApoE-/- mice, which resembled the findings observed in macrophages.

  3. LPS may increase Ac-LDL uptake and enhance CD204 expression through MAPK/ERK activation in bone marrow-derived macrophages.

  4. The low magnitude of opsonin-independent phagocytosis of Escherichia coli and unimpaired phagocytosis of Staphylococcus aureus in SR-A- or CD36-deficient macrophages indicate that the defect in this process might not be responsible for the reported impaired bacteria clearance in mice deficient in these receptors.

  5. Data (including data from studies conducted in cells from knockout mice) suggest that signaling via Lpar1, Cd14, and Scara1 mediates uptake of oxidized LDL by macrophages leading to foam cell formation; lysophosphatidic acid (LPA) induces expression of Cd14 and Scara1 in macrophages. (Lpar1 = LPA receptor 1; Cd14 = monocyte differentiation antigen CD14; Scara1 = scavenger receptor class A type I)

  6. Common damage-associated molecular patterns (DAMPs) were internalized through the class A scavenger receptors MSR1 and MARCO in vitro. In ischemic murine brain, DAMP internalization was largely mediated by MSR1. Combined deficiency for Msr1 and Marco in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.

  7. PTX2 was identified PTX2 as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.

  8. this study shows that Msr1 functions as co-receptor along with TLRs for HMGB1 in M1-type inflammatory macrophages

  9. Our findings demonstrated that ClC-3 deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK/p38 MAPK dependent SR-A expression and foam cell formation

  10. FAP-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.

  11. Macrophages regulate FX plasma levels in an SR-AI-dependent manner.

  12. The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.

  13. these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.

  14. plays an important role in the normative inflammatory lung response to organic dust extract

  15. Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.

  16. Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta to SR-A, thereby promoting glial phagocytosis of Abeta oligomer in an immortalized microglia cell line.

  17. SR-A does not induce cytokine production, but mediates inhibition of LPS-stimulated production of IL-6 and IL-12

  18. The antagonism between SR-A and RAGE contributes to the pathogenesis of diabetic retinopathy by nurturing a disease-prone macrophage phenotype.

  19. our data indicate that SR-A localizes in LRs and that LRs are required to couple SR-A to PLA2 activation during SRA-mediated macrophage attachment.

  20. the contribution of SR-A and CD36 scavenger receptors in the control of infection of mice by S. aureus.

Macrophage Scavenger Receptor 1 (MSR1) Antigen Profile

Protein Summary

This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.

Gene names and symbols associated with MSR1

  • macrophage scavenger receptor 1 (MSR1) antibody
  • macrophage scavenger receptor 1 (Msr1) antibody
  • CD204 antibody
  • MRS-A antibody
  • MSR antibody
  • MSR-A antibody
  • MSR1 antibody
  • phSR1 antibody
  • phSR2 antibody
  • RGD1564316 antibody
  • Scara1 antibody
  • Scvr antibody
  • SR-A antibody
  • SR-AI antibody
  • SR-AII antibody
  • SRA antibody

Protein level used designations for MSR1

macrophage acetylated LDL receptor I and II , macrophage scavenger receptor type III , macrophage scavenger receptor types I and II , scavenger receptor class A member 1 , scavenger receptor class A, member 1 , SR-A , scavenger receptor type A , macrophage scavenger receptor 1 , macrophage scavenger receptor type I , macrophage scavenger receptor types I and II-like

GENE ID SPECIES
4481 Homo sapiens
20288 Mus musculus
281311 Bos taurus
464003 Pan troglodytes
482891 Canis lupus familiaris
498638 Rattus norvegicus
709365 Macaca mulatta
100009067 Oryctolagus cuniculus
100386222 Callithrix jacchus
100602129 Nomascus leucogenys
100511665 Sus scrofa
100731555 Cavia porcellus
100053116 Equus caballus
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