Macrophage Scavenger Receptor 1 Products
(Macrophage Scavenger Receptor 1 (MSR1))
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This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008].
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Featured Macrophage Scavenger Receptor 1 Categories
Macrophage Scavenger Receptor 1 Antibodies
High quality antibodies with extensive validation data.
Macrophage Scavenger Receptor 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Macrophage Scavenger Receptor 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Macrophage Scavenger Receptor 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Sheep
Application
WB, ELISA, FACS, IHC (fro), IF (cc), IF (p), IHC (p)
Validations
- (5)
Cat. No.
ABIN872905
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC, Neut
Validations
- (5)
Cat. No.
ABIN7193254
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6263400
Quantity
100 μL
Datasheet
Datasheet
Recommended Macrophage Scavenger Receptor 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957614
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968418
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973534
Quantity
96 tests
Datasheet
Datasheet
Recommended Macrophage Scavenger Receptor 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275296
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311469
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7321106
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Macrophage Scavenger Receptor 1 products
: "Mechanism of TGF-β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis." in: Experimental and therapeutic medicine, Vol. 20, Issue 2, pp. 1541-1549, (2020) (PubMed).: "Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development." in: Cell reports, Vol. 31, Issue 12, pp. 107802, (2020) (PubMed).
: "Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study." in: Nature communications, Vol. 11, Issue 1, pp. 1911, (2020) (PubMed).
: "Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis." in: Arthritis research & therapy, Vol. 20, Issue 1, pp. 46, (2018) (PubMed).
: "Effect of Orally Administered Atractylodes macrocephala Koidz Water Extract on Macrophage and T Cell Inflammatory Response in Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 4041873, (2018) (PubMed).
: "Bushfire smoke is pro-inflammatory and suppresses macrophage phagocytic function." in: Scientific reports, Vol. 8, Issue 1, pp. 13424, (2018) (PubMed).
: "Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation." in: International immunology, Vol. 29, Issue 2, pp. 59-70, (2017) (PubMed).
: "Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1516-1525, (2017) (PubMed).
: "Phagocytosis and Inflammation: Exploring the effects of the components of E-cigarette vapor on macrophages." in: Physiological reports, Vol. 5, Issue 16, (2017) (PubMed).
: "Combination of plasma HA and circulating M2-like monocytes may serve as a diagnostic marker for breast cancer." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3522-3530, (2017) (PubMed).
Synonyms and alternative names related to Macrophage Scavenger Receptor 1
macrophage scavenger receptor 1 (MSR1), macrophage scavenger receptor 1 (Msr1), scavenger receptor class A member 5 (SCARA5), CD204, MRS-A, MSR, MSR-A, MSR1, phSR1, phSR2, RGD1564316, SCARA1, Scara1, Scvr, SR-A, SR-AI, SR-AII, SRAProtein level used designations for Macrophage Scavenger Receptor 1
- macrophage acetylated LDL receptor I and II
- macrophage scavenger receptor type III
- macrophage scavenger receptor types I and II
- scavenger receptor class A member 1
- scavenger receptor class A, member 1
- SR-A
- scavenger receptor type A
- macrophage scavenger receptor 1
- macrophage scavenger receptor type I
- macrophage scavenger receptor types I and II-like
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