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Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Additionally we are shipping MDH2 Antibodies (82) and MDH2 Kits (17) and many more products for this protein.
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Med24 (show MED22 Proteins) and Mdh2 are required for Drosophila larval salivary gland cell death
loss-of-function mutations in MDH2 are also associated with severe neurological clinical presentations in children
Data indicate that acetyl-CoA (show LPCAT2 Proteins) acetyltransferase (ACAT1 (show ACAT1 Proteins)) and malate dehydrogenase (MDH2 (show MDH Proteins)) are involved in various drug-resistance-forming mechanisms.
Segregation of the mutation with disease and absence of MDH2 in mutated tumors revealed MDH2 as a novel pheochromocytoma/paraganglioma susceptibility gene.
L-2-hydroxyglutarate accumulates as a result of a deficiency in FAD (show BRCA2 Proteins)-linked L-2-hydroxyglutarate dehydrogenase (show L2HGDH Proteins). mitochondrial L-malate dehydrogenase (show ME1 Proteins) is responsible for the excretion of L-2-hydroxyglutarate in this condition.
Macromolecular crowding effects on MDH (show MDH1 Proteins) depend on the isozyme, reaction direction, and crowding agent. Crowding increases Km of mitochondrial MDH (show MDH1 Proteins) for malate oxidation.
The acetylation of MDH2 was affected by the cellular energy state and subsequently regulated adipogenic differentiation.
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.
mitochondrial malate dehydrogenase 2b
, mitochondrial malate dehydrogenase
, mitochondrial malate dehydrogenase 2, NAD
, malate dehydrogenase, mitochondrial
, malate dehydrogenase 2, mitochondrial