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MCFD2 Proteins

(Multiple Coagulation Factor Deficiency 2 (MCFD2))

This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1\; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D)\; a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010].

recommended

MCFD2 Protein (AA 27-146) (His tag) (ABIN3083576)

Crystallography grade MCFD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys

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recommended

MCFD2 Protein (AA 27-145) (His tag) (ABIN3126486)

Crystallography grade MCFD2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys

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recommended

MCFD2 Protein (AA 27-146) (T7 tag) (ABIN666930)

MCFD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS

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MCFD2 Proteins by Grade

Find MCFD2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 Proteins by Origin

Find MCFD2 Proteins for a variety of species such as anti-Human MCFD2, anti-Mouse MCFD2, anti-Rat MCFD2. The species listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 Proteins by Source

Find MCFD2 Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 Proteins by Protein Type

Find MCFD2 Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 Proteins by Application

Find MCFD2 Proteins validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MCFD2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MCFD2 Protein (AA 27-146) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3083576

Quantity 1 mg

Datasheet Datasheet

MCFD2 Protein (AA 27-145) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3126486

Quantity 1 mg

Datasheet Datasheet

MCFD2 Protein (AA 27-146) (T7 tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN666930

Quantity 100 μg

Datasheet Datasheet

MCFD2 Protein (AA 1-146) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310538

Quantity 10 μg

Datasheet Datasheet

MCFD2 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2725609

Quantity 20 μg

Datasheet Datasheet

MCFD2 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2130495

Quantity 100 μg

Datasheet Datasheet

MCFD2 Protein (AA 27-145) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1637758

Quantity 1 mg

Datasheet Datasheet

Aliases for MCFD2 Proteins

multiple coagulation factor deficiency 2 (MCFD2) Proteins
multiple coagulation factor deficiency 2 (mcfd2) Proteins
multiple coagulation factor deficiency 2 L homeolog (mcfd2.L) Proteins
multiple coagulation factor deficiency 2 (Mcfd2) Proteins
1810021C21Rik Proteins
DKFZp469B098 Proteins
F5F8D Proteins
F5f8d Proteins
F5F8D2 Proteins
hm:zeh1186 Proteins
LMAN1IP Proteins
Lman1ip Proteins
MCFD2 Proteins
SDNSF Proteins
Sdnsf Proteins
wu:fc23b10 Proteins
wu:fd50d08 Proteins
zgc:103713 Proteins
zgc:109915 Proteins

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MCFD2 Proteins by Grade

MCFD2 Proteins by Origin

MCFD2 Proteins by Source

MCFD2 Proteins by Protein Type

MCFD2 Proteins by Application

Popular MCFD2 Proteins

Aliases for MCFD2 Proteins

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